Evidence map›Paper›PMID 36142853›Full record

ArticleInternational journal of molecular sciences2022

Integrins Increase Sarcoplasmic Reticulum Activity for Excitation-Contraction Coupling in Human Stem Cell-Derived Cardiomyocytes.

Brian X Wang, Christopher Kane, Laura Nicastro, Oisín King, Worrapong Kit-Anan, Barrett Downing, Graziano Deidda, Liam S Couch, Christian Pinali, Anna Mitraki and 2 more

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.3field-weighted citation impact, top 51% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 3 countries.

Brian X WangNational Heart & Lung Institute, Imperial College London, London SW7 2AZ, UK.
Christopher KaneNational Heart & Lung Institute, Imperial College London, London SW7 2AZ, UK.
Laura NicastroNational Heart & Lung Institute, Imperial College London, London SW7 2AZ, UK.
Oisín KingNational Heart & Lung Institute, Imperial College London, London SW7 2AZ, UK.
Worrapong Kit-AnanNational Heart & Lung Institute, Imperial College London, London SW7 2AZ, UK.
Barrett DowningNational Heart & Lung Institute, Imperial College London, London SW7 2AZ, UK.
Graziano DeiddaInstitute of Electronic Structure and Laser (IESL), Foundation for Research and Technology-Hellas (FORTH), 700 13 Heraklion, Greece.ORCID 0000-0003-0299-1226
Liam S CouchNational Heart & Lung Institute, Imperial College London, London SW7 2AZ, UK.ORCID 0000-0002-9926-2574
Christian PinaliDivision of Cardiovascular Sciences, University of Manchester, Manchester M13 9NT, UK.
Anna MitrakiInstitute of Electronic Structure and Laser (IESL), Foundation for Research and Technology-Hellas (FORTH), 700 13 Heraklion, Greece.
Kenneth T MacLeodNational Heart & Lung Institute, Imperial College London, London SW7 2AZ, UK.
Cesare M TerraccianoNational Heart & Lung Institute, Imperial College London, London SW7 2AZ, UK.ORCID 0000-0003-2761-0696
Imperial College London · GBUniversity of Crete · GRBayer (France) · FRUniversity of Manchester · GB

Funding

British Heart Foundation FS/13/46/30282British Heart Foundation FS/16/76/32409British Heart Foundation FS/18/4/33310Wellcome Trust
6 · The paper itself

Abstract

Engagement of the sarcoplasmic reticulum (SR) Ca

Indexed as

Induced Pluripotent Stem CellsSarcoplasmic ReticulumArginineAspartic AcidCaffeineCalciumFibronectinsGlycineHumansIntegrinsLigandsMyocytes, CardiacRyanodine Receptor Calcium Release ChannelArginineAspartic AcidCaffeineCalciumFibronectinsGlycineIntegrinsLigandsRyanodine Receptor Calcium Release ChannelCa2+ cyclingcardiomyocytefibrosisintegrinryanodine receptorsarcoplasmic reticulumstem cell

Identifiers

PMID36142853
PMCPMC9504605
OpenAlexW4296462912

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.