Evidence map›Paper›PMID 36142845›Full record

ArticleInternational journal of molecular sciences2022

Y98 Mutation Leads to the Loss of RsfS Anti-Association Activity in

Bulat Fatkhullin, Alexander Golubev, Natalia Garaeva, Shamil Validov, Azat Gabdulkhakov, Marat Yusupov

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 44% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Mechanistic insights intobioRxiv : the preprint server for biology · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 2 countries.

Bulat FatkhullinInstitute of Protein Research, Russian Academy of Science, 142290 Pushchino, Russia.
Alexander GolubevLaboratory for Structural Analysis of Biomacromolecules, Kazan Scientific Center of Russian Academy of Sciences, 420111 Kazan, Russia.
Natalia GaraevaLaboratory for Structural Analysis of Biomacromolecules, Kazan Scientific Center of Russian Academy of Sciences, 420111 Kazan, Russia.
Shamil ValidovLaboratory for Structural Analysis of Biomacromolecules, Kazan Scientific Center of Russian Academy of Sciences, 420111 Kazan, Russia.
Azat GabdulkhakovInstitute of Protein Research, Russian Academy of Science, 142290 Pushchino, Russia.ORCID 0000-0003-1016-5936
Marat YusupovDepartment of Integrated Structural Biology, Institute of Genetics and Molecular and Cellular Biology, INSERM, U964, CNRS, UMR7104, University of Strasbourg, 67400 Illkirch Graffenstaden, France.
Centre National de la Recherche Scientifique · FRKazan Federal University · RUA.E. Arbuzov Institute of Organic and Physical Chemistry · RUInstitute of Protein Research · RU

Funding

Government assignment for FRC Kazan Scientific Center of Russian Academy of Sciences
6 · The paper itself

Abstract

Ribosomal silencing factor S (RsfS) is a conserved protein that plays a role in the mechanisms of ribosome shutdown and cell survival during starvation. Recent studies demonstrated the involvement of RsfS in the biogenesis of the large ribosomal subunit. RsfS binds to the uL14 ribosomal protein on the large ribosomal subunit and prevents its association with the small subunit. Here, we estimated the contribution of RsfS amino acid side chains at the interface between RsfS and uL14 to RsfS anti-association function in

Indexed as

BiotinStaphylococcus aureusAmino AcidsBacterial ProteinsMutationRibosomal ProteinsRibosomesSucroseAmino AcidsBacterial ProteinsBiotinRibosomal ProteinsSucrosehibernation factormaturation factorribosomeRsfSStaphylococcus aureus

Identifiers

PMID36142845
PMCPMC9503621
OpenAlexW4296351435

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.