Evidence map›Paper›PMID 36142836›Full record

ArticleInternational journal of molecular sciences2022

Chronic Ouabain Prevents Radiation-Induced Reduction in the α2 Na,K-ATPase Function in the Rat Diaphragm Muscle.

Violetta V Kravtsova, Arina A Fedorova, Maria V Tishkova, Alexandra A Livanova, Oleg V Vetrovoy, Alexander G Markov, Vladimir V Matchkov, Igor I Krivoi

Open access · goldAbstract read
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In one paragraph

Article in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 48% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 2 countries.

Violetta V KravtsovaDepartment of General Physiology, St. Petersburg State University, 199034 St. Petersburg, Russia.
Arina A FedorovaDepartment of General Physiology, St. Petersburg State University, 199034 St. Petersburg, Russia.ORCID 0000-0001-8080-7426
Maria V TishkovaDepartment of General Physiology, St. Petersburg State University, 199034 St. Petersburg, Russia.
Alexandra A LivanovaDepartment of General Physiology, St. Petersburg State University, 199034 St. Petersburg, Russia.
Oleg V VetrovoyPavlov Institute of Physiology, Russian Academy of Sciences, 199034 St. Petersburg, Russia.ORCID 0000-0002-1860-5935
Alexander G MarkovDepartment of General Physiology, St. Petersburg State University, 199034 St. Petersburg, Russia.
Vladimir V MatchkovDepartment of Biomedicine, Aarhus University, C 8000 Aarhus, Denmark.ORCID 0000-0002-3303-1095
Igor I KrivoiDepartment of General Physiology, St. Petersburg State University, 199034 St. Petersburg, Russia.ORCID 0000-0002-2690-9226
St Petersburg University · RUAarhus University · DK

Funding

Russian Science Foundation 18-15-00043
6 · The paper itself

Abstract

The damaging effect of ionizing radiation (IR) on skeletal muscle Na,K-ATPase is an open field of research. Considering a therapeutic potential of ouabain, a specific ligand of the Na,K-ATPase, we tested its ability to protect against the IR-induced disturbances of Na,K-ATPase function in rat diaphragm muscle that co-expresses the α1 and α2 isozymes of this protein. Male Wistar rats (

Indexed as

OuabainSodium-Potassium-Exchanging ATPaseAnimalsCorticosteroneDiaphragmInterleukin-6IsoenzymesLigandsMaleMuscle, SkeletalRatsRats, WistarSaline SolutionSodiumCorticosteroneInterleukin-6IsoenzymesLigandsOuabainSaline SolutionSodiumSodium-Potassium-Exchanging ATPaseionizing radiationNa,K-ATPase isozymesouabainresting membrane potentialskeletal muscle

Identifiers

PMID36142836
PMCPMC9505176
OpenAlexW4296355293

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.