Evidence map›Paper›PMID 36142828›Full record

ArticleInternational journal of molecular sciences2022

A Novel L-Phenylalanine Dipeptide Inhibits the Growth and Metastasis of Prostate Cancer Cells via Targeting DUSP1 and TNFSF9.

Lanlan Li, Mingfei Yang, Jia Yu, Sha Cheng, Mashaal Ahmad, Caihong Wu, Xinwei Wan, Bixue Xu, Yaacov Ben-David, Heng Luo

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.6field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 19 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Lanlan LiState Key Laboratory for Functions and Applications of Medicinal Plants, Guizhou Medical University, Guiyang 550014, China.
Mingfei YangState Key Laboratory for Functions and Applications of Medicinal Plants, Guizhou Medical University, Guiyang 550014, China.
Jia YuState Key Laboratory for Functions and Applications of Medicinal Plants, Guizhou Medical University, Guiyang 550014, China.
Sha ChengState Key Laboratory for Functions and Applications of Medicinal Plants, Guizhou Medical University, Guiyang 550014, China.
Mashaal AhmadState Key Laboratory for Functions and Applications of Medicinal Plants, Guizhou Medical University, Guiyang 550014, China.
Caihong WuState Key Laboratory for Functions and Applications of Medicinal Plants, Guizhou Medical University, Guiyang 550014, China.
Xinwei WanState Key Laboratory for Functions and Applications of Medicinal Plants, Guizhou Medical University, Guiyang 550014, China.
Bixue XuState Key Laboratory for Functions and Applications of Medicinal Plants, Guizhou Medical University, Guiyang 550014, China.
Yaacov Ben-DavidState Key Laboratory for Functions and Applications of Medicinal Plants, Guizhou Medical University, Guiyang 550014, China.
Heng LuoState Key Laboratory for Functions and Applications of Medicinal Plants, Guizhou Medical University, Guiyang 550014, China.ORCID 0000-0001-6839-1659
Guiyang Medical University · CN

Funding

Guizhou province "Hundred" level innovative talent training project QKHPTRC-GCC[2022]034-1The main projects of the Natural Science Foundation of Guizhou province No. QKHJC-ZK [2022]ZD031The Science and Technology Planning Project of Guizhou Province No. QKHZC [2022]194
6 · The paper itself

Abstract

Prostate cancer (PCa) is a common malignant cancer of the urinary system. Drug therapy, chemotherapy, and radical prostatectomy are the primary treatment methods, but drug resistance and postoperative recurrence often occur. Therefore, seeking novel anti-tumor compounds with high efficiency and low toxicity from natural products can produce a new tumor treatment method. Matijin-Su [

Indexed as

Biological ProductsProstatic Neoplasms4-1BB LigandApoptosisCell Line, TumorCell MovementCell ProliferationDipeptidesDual Specificity Phosphatase 1HumansInterleukin-6MaleMolecular Docking SimulationPhenylalanineProteomicsSerpin E24-1BB LigandBiological ProductsDipeptidesDual Specificity Phosphatase 1DUSP1 protein, humanInterleukin-6PhenylalanineSerpin E2TNFSF9 protein, humancell growth and metastasisDUSP1HXL131L-phenylalanine dipeptideprostate cancerproteomicsTNFSF9

Identifiers

PMID36142828
PMCPMC9504056
OpenAlexW4296352112

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.