Evidence map›Paper›PMID 36142775›Full record

ReviewInternational journal of molecular sciences2022

Review of the Current State of Freely Accessible Web Tools for the Analysis of 16S rRNA Sequencing of the Gut Microbiome.

Jerald Conrad Ibal, Yeong-Jun Park, Min-Kyu Park, Jooeun Lee, Min-Chul Kim, Jae-Ho Shin

Abstract readReview
In one paragraph

Review in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Opioid Use and Gut Dysbiosis in Cancer Pain Patients.International journal of molecular sciences · 2024
    Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Jerald Conrad IbalNGS Core Facility, Kyungpook National University, Daehak-ro 80, Daegu 41566, Korea.
Yeong-Jun ParkNGS Core Facility, Kyungpook National University, Daehak-ro 80, Daegu 41566, Korea.
Min-Kyu ParkNGS Core Facility, Kyungpook National University, Daehak-ro 80, Daegu 41566, Korea.
Jooeun LeeNGS Core Facility, Kyungpook National University, Daehak-ro 80, Daegu 41566, Korea.
Min-Chul KimNGS Core Facility, Kyungpook National University, Daehak-ro 80, Daegu 41566, Korea.
Jae-Ho ShinNGS Core Facility, Kyungpook National University, Daehak-ro 80, Daegu 41566, Korea.ORCID 0000-0001-6450-9787

Funding

Korea Basic Science Institute NRF-2020R1A6A3A01100541Korea Basic Science Institute NRF-2021R1A6C101A416The project to train professional personnel in biological materials by the Ministry of Environment.
6 · The paper itself

Abstract

Owing to the emergence and improvement of high-throughput technology and the associated reduction in costs, next-generation sequencing (NGS) technology has made large-scale sampling and sequencing possible. With the large volume of data produced, the processing and downstream analysis of data are important for ensuring meaningful results and interpretation. Problems in data analysis may be encountered if researchers have little experience in using programming languages, especially if they are clinicians and beginners in the field. A strategy for solving this problem involves ensuring easy access to commercial software and tools. Here, we observed the current status of free web-based tools for microbiome analysis that can help users analyze and handle microbiome data effortlessly. We limited our search to freely available web-based tools and identified MicrobiomeAnalyst, Mian, gcMeta, VAMPS, and Microbiome Toolbox. We also highlighted the various analyses that each web tool offers, how users can analyze their data using each web tool, and noted some of their limitations. From the abovementioned list, gcMeta, VAMPS, and Microbiome Toolbox had several issues that made the analysis more difficult. Over time, as more data are generated and accessed, more users will analyze microbiome data. Thus, the availability of free and easily accessible web tools can enable the easy use and analysis of microbiome data, especially for those users with less experience in using command-line interfaces.

Indexed as

Gastrointestinal MicrobiomeMicrobiotaHigh-Throughput Nucleotide SequencingRNA, Ribosomal, 16SSoftwareRNA, Ribosomal, 16S16S rRNAgut microbiomemicrobiome analysisnext-generation sequencingweb-based tool

Identifiers

PMID36142775
PMCPMC9501225

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.