Evidence map›Paper›PMID 36142766›Full record

ArticleInternational journal of molecular sciences2022

Analysis of Circulating Tumor and Cancer Stem Cells Provides New Opportunities in Diagnosis and Treatment of Small Cell Lung Cancer.

Evgenii G Skurikhin, Natalia Ermakova, Mariia Zhukova, Olga Pershina, Edgar Pan, Angelina Pakhomova, Lena Kogai, Victor Goldberg, Elena Simolina, Victoria Skurikhina and 5 more

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.6field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Article
  3. PD-L1Journal of translational medicine · 2025
    Article
  4. In Vitro Study of Cancer Stem Cells and Reprogrammed CD3Bulletin of experimental biology and medicine · 2025
    Article
  5. Article
  6. Article
  7. Cell Therapy with Human Reprogrammed CD8International journal of molecular sciences · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 6 institutions in 2 countries.

Evgenii G SkurikhinLaboratory of Regenerative Pharmacology, Goldberg ED Research Institute of Pharmacology and Regenerative Medicine, Tomsk National Research Medical Centre of the Russian Academy of Sciences, Lenin, 3, 634028 Tomsk, Russia.
Natalia ErmakovaLaboratory of Regenerative Pharmacology, Goldberg ED Research Institute of Pharmacology and Regenerative Medicine, Tomsk National Research Medical Centre of the Russian Academy of Sciences, Lenin, 3, 634028 Tomsk, Russia.
Mariia ZhukovaLaboratory of Regenerative Pharmacology, Goldberg ED Research Institute of Pharmacology and Regenerative Medicine, Tomsk National Research Medical Centre of the Russian Academy of Sciences, Lenin, 3, 634028 Tomsk, Russia.ORCID 0000-0002-8146-2279
Olga PershinaLaboratory of Regenerative Pharmacology, Goldberg ED Research Institute of Pharmacology and Regenerative Medicine, Tomsk National Research Medical Centre of the Russian Academy of Sciences, Lenin, 3, 634028 Tomsk, Russia.ORCID 0000-0002-0468-0272
Edgar PanLaboratory of Regenerative Pharmacology, Goldberg ED Research Institute of Pharmacology and Regenerative Medicine, Tomsk National Research Medical Centre of the Russian Academy of Sciences, Lenin, 3, 634028 Tomsk, Russia.ORCID 0000-0002-2163-7647
Angelina PakhomovaLaboratory of Regenerative Pharmacology, Goldberg ED Research Institute of Pharmacology and Regenerative Medicine, Tomsk National Research Medical Centre of the Russian Academy of Sciences, Lenin, 3, 634028 Tomsk, Russia.ORCID 0000-0003-0725-1323
Lena KogaiLaboratory of Regenerative Pharmacology, Goldberg ED Research Institute of Pharmacology and Regenerative Medicine, Tomsk National Research Medical Centre of the Russian Academy of Sciences, Lenin, 3, 634028 Tomsk, Russia.
Victor GoldbergCancer Research Institute, Tomsk National Research Medical Center, Kooperativny, 5, 634009 Tomsk, Russia.
Elena SimolinaCancer Research Institute, Tomsk National Research Medical Center, Kooperativny, 5, 634009 Tomsk, Russia.
Victoria SkurikhinaMinistry of Health of the Russian Federation, Siberian State Medical University, Moskovski, 2, 634050 Tomsk, Russia.
Darius WideraStem Cell Biology and Regenerative Medicine Group, School of Pharmacy, Whiteknights Campus, Reading RG6 6AP, UK.ORCID 0000-0003-1686-130X
Aslan KubatievInstitute of General Pathology and Pathophysiology, 125315 Moscow, Russia.
Sergey G MorozovInstitute of General Pathology and Pathophysiology, 125315 Moscow, Russia.
Nikolai KushlinskiiBlokhin National Medical Research Center of Oncology, 115522 Moscow, Russia.
Alexander DygaiLaboratory of Regenerative Pharmacology, Goldberg ED Research Institute of Pharmacology and Regenerative Medicine, Tomsk National Research Medical Centre of the Russian Academy of Sciences, Lenin, 3, 634028 Tomsk, Russia.
Russian Academy of Sciences · RUResearch Institute of General Pathology and Pathophysiology, the Russian Academy of Medical Sciences · RUTomsk National Research Medical Center · RUNational Medical Research Center of Cardiology · RUSiberian State Medical University · RUUniversity of Reading · GB

Funding

Ministry of Science and Higher Education Russian Federation 075-15-2020-773
6 · The paper itself

Abstract

Current methods for diagnosis and treatment of small cell lung cancer (SCLC) have only a modest efficacy. In this pilot study, we analyzed circulating tumor cells (CTCs) and cancer stem cells (CSCs) in patients with SCLC to search for new diagnostic and prognostic markers and novel approaches to improve the treatment of the disease. In other forms of lung cancer, we showed a heterogeneity of blood CTCs and CSCs populations, as well as changes in other cell populations (ALDH

Indexed as

Lung NeoplasmsNeoplastic Cells, CirculatingSmall Cell Lung CarcinomaB7 AntigensB7-H1 AntigenEpidermal Growth FactorHumansNeoplastic Stem CellsNivolumabPilot ProjectsProgrammed Cell Death 1 ReceptorB7 AntigensB7-H1 AntigenCD276 protein, humanEpidermal Growth FactorNivolumabProgrammed Cell Death 1 Receptorcancer stem cellscirculating tumor cellsreprogrammed CD8+ T-lymphocytessmall cell lung cancer

Identifiers

PMID36142766
PMCPMC9503899
OpenAlexW4296356060

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.