Evidence map›Paper›PMID 36142727›Full record

ArticleInternational journal of molecular sciences2022

Recognition Memory Induces Natural LTP-like Hippocampal Synaptic Excitation and Inhibition.

Irene Sánchez-Rodríguez, Sara Temprano-Carazo, Danko Jeremic, Jose Maria Delgado-Garcia, Agnès Gruart, Juan D Navarro-López, Lydia Jiménez-Díaz

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
2.5field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 27 citations in OpenAlex.

  1. Neuronal TDP-43 regulates myelin formation via neurexin 1 mRNA stabilization.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Neural Correlates and Molecular Mechanisms of Memory and Learning.International journal of molecular sciences · 2024
    Article
  7. Review
  8. Article
  9. Review
  10. Article
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Irene Sánchez-RodríguezNeurophysiology & Behavior Laboratory, Regional Centre for Biomedical Research (CRIB), School of Medicine of Ciudad Real, University of Castilla-La Mancha, 13071 Ciudad Real, Spain.
Sara Temprano-CarazoNeurophysiology & Behavior Laboratory, Regional Centre for Biomedical Research (CRIB), School of Medicine of Ciudad Real, University of Castilla-La Mancha, 13071 Ciudad Real, Spain.
Danko JeremicNeurophysiology & Behavior Laboratory, Regional Centre for Biomedical Research (CRIB), School of Medicine of Ciudad Real, University of Castilla-La Mancha, 13071 Ciudad Real, Spain.ORCID 0000-0001-9495-972X
Jose Maria Delgado-GarciaDivision of Neurosciences, University Pablo de Olavide, 41013 Seville, Spain.ORCID 0000-0001-7369-4195
Agnès GruartDivision of Neurosciences, University Pablo de Olavide, 41013 Seville, Spain.
Juan D Navarro-LópezNeurophysiology & Behavior Laboratory, Regional Centre for Biomedical Research (CRIB), School of Medicine of Ciudad Real, University of Castilla-La Mancha, 13071 Ciudad Real, Spain.ORCID 0000-0002-1877-7833
Lydia Jiménez-DíazNeurophysiology & Behavior Laboratory, Regional Centre for Biomedical Research (CRIB), School of Medicine of Ciudad Real, University of Castilla-La Mancha, 13071 Ciudad Real, Spain.ORCID 0000-0001-9121-0334
University of Castilla-La Mancha · ESUniversidad Pablo de Olavide · ES

Funding

JCCM/ERDF - A way of making Europe SBPLY/21/180501/000150MCIN/AEI/10.13039/501100011033 PID2020-115823-GB100Spanish Ministerio de Ciencia, Innovación y Universidades BFU2017-82494-P
6 · The paper itself

Abstract

Synaptic plasticity is a cellular process involved in learning and memory by which specific patterns of neural activity adapt the synaptic strength and efficacy of the synaptic transmission. Its induction is governed by fine tuning between excitatory/inhibitory synaptic transmission. In experimental conditions, synaptic plasticity can be artificially evoked at hippocampal CA1 pyramidal neurons by repeated stimulation of Schaffer collaterals. However, long-lasting synaptic modifications studies during memory formation in physiological conditions in freely moving animals are very scarce. Here, to study synaptic plasticity phenomena during recognition memory in the dorsal hippocampus, field postsynaptic potentials (fPSPs) evoked at the CA3-CA1 synapse were recorded in freely moving mice during object-recognition task performance. Paired pulse stimuli were applied to

Indexed as

HippocampusNeuronal PlasticityAnimalsCA1 Region, Hippocampalgamma-Aminobutyric AcidMicePotassiumSynapsesSynaptic Transmissiongamma-Aminobutyric AcidPotassiumexcitatory/inhibitory LTPfreely moving miceGirKhippocampusrecognition memorysynaptic plasticity

Identifiers

PMID36142727
PMCPMC9501019
OpenAlexW4296355836

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.