Evidence map›Paper›PMID 36142698›Full record

ArticleInternational journal of molecular sciences2022

Evaluation of Anti-

Juliana Ribeiro Reynaldo, Kátia Monteiro Novack, Lucas Resende Dutra Sousa, Paula Melo de Abreu Vieira, Tatiane Roquete Amparo, Gustavo Henrique Bianco de Souza, Luiz Fernando Medeiros Teixeira, Ana Paula Moreira Barboza, Bernardo Ruegger Almeida Neves, Meiry Edivirges Alvarenga and 2 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 50% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 1 country.

Juliana Ribeiro ReynaldoDepartment of Chemistry, Federal University of Ouro Preto (UFOP), Ouro Preto 35400-000, MG, Brazil.
Kátia Monteiro NovackDepartment of Chemistry, Federal University of Ouro Preto (UFOP), Ouro Preto 35400-000, MG, Brazil.ORCID 0000-0002-0644-9197
Lucas Resende Dutra SousaLaboratory of Morphopathology, Center for Research in Biological Sciences, Federal University of Ouro Preto (UFOP), Morro do Cruzeiro Campus, Ouro Preto 35400-000, MG, Brazil.
Paula Melo de Abreu VieiraLaboratory of Morphopathology, Center for Research in Biological Sciences, Federal University of Ouro Preto (UFOP), Morro do Cruzeiro Campus, Ouro Preto 35400-000, MG, Brazil.ORCID 0000-0001-7033-7686
Tatiane Roquete AmparoPostgraduate Program in Pharmaceutical Science, Federal University of Ouro Preto (UFOP), Morro do Cruzeiro Campus, Ouro Preto 35400-000, MG, Brazil.ORCID 0000-0002-6426-7113
Gustavo Henrique Bianco de SouzaPostgraduate Program in Pharmaceutical Science, Federal University of Ouro Preto (UFOP), Morro do Cruzeiro Campus, Ouro Preto 35400-000, MG, Brazil.ORCID 0000-0002-1548-3274
Luiz Fernando Medeiros TeixeiraPostgraduate Program in Pharmaceutical Science, Federal University of Ouro Preto (UFOP), Morro do Cruzeiro Campus, Ouro Preto 35400-000, MG, Brazil.
Ana Paula Moreira BarbozaPhysics Department, Federal University of Ouro Preto (UFOP), Morro do Cruzeiro Campus, Ouro Preto 35400-000, MG, Brazil.
Bernardo Ruegger Almeida NevesDepartment of Physics, Federal University of Minas Gerais (UFMG), Belo Horizonte 31270-901, MG, Brazil.ORCID 0000-0003-0464-4754
Meiry Edivirges AlvarengaInstitute of Chemistry, Federal University of Goiás (UFG), Samambaia Campus, Goiânia 74690-900, GO, Brazil.
Felipe Terra MartinsInstitute of Chemistry, Federal University of Goiás (UFG), Samambaia Campus, Goiânia 74690-900, GO, Brazil.
Viviane Martins Rebello Dos SantosDepartment of Chemistry, Federal University of Ouro Preto (UFOP), Ouro Preto 35400-000, MG, Brazil.ORCID 0000-0002-0144-9518
Universidade Federal de Ouro Preto · BRUniversidade Federal de Goiás · BRUniversidade Federal de Minas Gerais · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Modified release systems depend on the selection of an appropriate agent capable of controlling the release of the drug, sustaining the therapeutic action over time, and/or releasing the drug at the level of a particular tissue or target organ. Polyethylene glycol 4000 (PEG 4000) is commonly employed in drug release formulations while polymethyl methacrylate (PMMA) is non-toxic and has a good solubility in organic solvents. This study aimed at the incorporation of ketoconazole in PMMA-g-PEG 4000 and its derivatives, thus evaluating its release profile and anti-

Indexed as

Candida albicansKetoconazoleAntifungal AgentsHumansPolyethylene GlycolsPolymethyl MethacrylateSolventsAntifungal AgentsKetoconazolepolyethylene glycol 4000Polyethylene GlycolsPolymethyl MethacrylateSolventsCandida albicansketoconazolePMMA-g-PEG 4000

Identifiers

PMID36142698
PMCPMC9504905
OpenAlexW4296280820

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.