Evidence map›Paper›PMID 36142682›Full record

ReviewInternational journal of molecular sciences2022

Nitric Oxide, Nitric Oxide Formers and Their Physiological Impacts in Bacteria.

Jinghua Chen, Lulu Liu, Weiwei Wang, Haichun Gao

Open access · goldAbstract readReview
In one paragraph

Review in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 46 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Nitric oxide tunes secreted metabolite bioactivity.bioRxiv : the preprint server for biology · 2025
    Article
  5. Review
  6. Review
  7. Article
  8. Emerging Resistance and Virulence Patterns inAntibiotics (Basel, Switzerland) · 2025
    Article
  9. Review
  10. Article
  11. Review
  12. Article
  13. ACS applied materials & interfaces · 2024
    Article
  14. Article
  15. Article
  16. Nitric Oxide in Fungi: Production and Function.Journal of fungi (Basel, Switzerland) · 2024
    Review
  17. Disparate Effects of Two Clerodane Diterpenes of Giant Goldenrod (International journal of molecular sciences · 2024
    Article
  18. Article
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Jinghua ChenInstitute of Microbiology, College of Life Sciences, Zhejiang University, Hangzhou 310058, China.
Lulu LiuInstitute of Microbiology, College of Life Sciences, Zhejiang University, Hangzhou 310058, China.ORCID 0000-0001-7394-9821
Weiwei WangInstitute of Microbiology, College of Life Sciences, Zhejiang University, Hangzhou 310058, China.
Haichun GaoInstitute of Microbiology, College of Life Sciences, Zhejiang University, Hangzhou 310058, China.ORCID 0000-0002-2647-6563
Zhejiang University · CN

Funding

National Natural Science Foundation of China 31930003
6 · The paper itself

Abstract

Nitric oxide (NO) is an active and critical nitrogen oxide in the microbe-driven nitrogen biogeochemical cycle, and is of great interest to medicine and the biological sciences. As a gas molecule prior to oxygen, NO respiration represents an early form of energy generation via various reactions in prokaryotes. Major enzymes for endogenous NO formation known to date include two types of nitrite reductases in denitrification, hydroxylamine oxidoreductase in ammonia oxidation, and NO synthases (NOSs). While the former two play critical roles in shaping electron transport pathways in bacteria, NOSs are intracellular enzymes catalyzing metabolism of certain amino acids and have been extensively studied in mammals. NO interacts with numerous cellular targets, most of which are redox-active proteins. Doing so, NO plays harmful and beneficial roles by affecting diverse biological processes within bacterial physiology. Here, we discuss recent advances in the field, including NO-forming enzymes, the molecular mechanisms by which these enzymes function, physiological roles of bacterial NOSs, and regulation of NO homeostasis in bacteria.

Indexed as

AmmoniaNitric OxideAmino AcidsAnimalsBacteriaMammalsNitrite ReductasesNitrogenNitrogen OxidesOxygenAmino AcidsAmmoniaNitric OxideNitrite ReductasesNitrogenNitrogen OxidesOxygenhemoproteinsnitric oxidenitric oxide forming enzymesnitric oxide synthaseNO signalingNO tolerance

Identifiers

PMID36142682
PMCPMC9500659
OpenAlexW4296281041

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.