Evidence map›Paper›PMID 36142670›Full record

ArticleInternational journal of molecular sciences2022

In Vitro Rescue of the Bile Acid Transport Function of ABCB11 Variants by CFTR Potentiators.

Elodie Mareux, Martine Lapalus, Amel Ben Saad, Renaud Zelli, Mounia Lakli, Yosra Riahi, Marion Almes, Manon Banet, Isabelle Callebaut, Jean-Luc Decout and 3 more

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.4field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 14 citations in OpenAlex.

  1. Trial
  2. Article
  3. Article
  4. Review
  5. Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 3 institutions in 1 country.

Elodie MareuxInserm UMR_S 1193, Physiopathogénèse et Traitement des Maladies du Foie, Université Paris-Saclay, FHU Hepatinov, 91400 Orsay, France.ORCID 0000-0002-0474-9217
Martine LapalusInserm UMR_S 1193, Physiopathogénèse et Traitement des Maladies du Foie, Université Paris-Saclay, FHU Hepatinov, 91400 Orsay, France.ORCID 0000-0002-7033-831X
Amel Ben SaadInserm UMR_S 1193, Physiopathogénèse et Traitement des Maladies du Foie, Université Paris-Saclay, FHU Hepatinov, 91400 Orsay, France.
Renaud ZelliUniversité Grenoble Alpes, CNRS, UMR CNRS 5063, DPM, 38000 Grenoble, France.
Mounia LakliInserm UMR_S 1193, Physiopathogénèse et Traitement des Maladies du Foie, Université Paris-Saclay, FHU Hepatinov, 91400 Orsay, France.
Yosra RiahiInserm UMR_S 1193, Physiopathogénèse et Traitement des Maladies du Foie, Université Paris-Saclay, FHU Hepatinov, 91400 Orsay, France.
Marion AlmesAssistance Publique-Hôpitaux de Paris, Pediatric Hepatology & Pediatric Liver Transplant Department, Reference Center for Rare Pediatric Liver Diseases, FILFOIE, ERN Rare-Liver, Faculté de Médecine Paris-Saclay, CHU Bicêtre, 94270 Le Kremlin-Bicêtre, France.
Manon BanetInserm UMR_S 1193, Physiopathogénèse et Traitement des Maladies du Foie, Université Paris-Saclay, FHU Hepatinov, 91400 Orsay, France.
Isabelle CallebautMuséum National d'Histoire Naturelle, UMR CNRS 7590, Institut de Minéralogie, de Physique des Matériaux et de Cosmochimie (IMPMC), Sorbonne Université, 75005 Paris, France.
Jean-Luc DecoutUniversité Grenoble Alpes, CNRS, UMR CNRS 5063, DPM, 38000 Grenoble, France.ORCID 0000-0001-7058-1304
Thomas FalguièresInserm UMR_S 1193, Physiopathogénèse et Traitement des Maladies du Foie, Université Paris-Saclay, FHU Hepatinov, 91400 Orsay, France.ORCID 0000-0003-2867-0500
Emmanuel JacqueminInserm UMR_S 1193, Physiopathogénèse et Traitement des Maladies du Foie, Université Paris-Saclay, FHU Hepatinov, 91400 Orsay, France.
Emmanuel GonzalesInserm UMR_S 1193, Physiopathogénèse et Traitement des Maladies du Foie, Université Paris-Saclay, FHU Hepatinov, 91400 Orsay, France.ORCID 0000-0002-1546-3193
Inserm · FRCentre National de la Recherche Scientifique · FRAssistance Publique – Hôpitaux de Paris · FR

Funding

Ministère de l'Enseignement Supérieur, de la Recherche et de l'Innovation Français; Association Maladie Foie Enfants, Malakoff, France; Filière de Santé Maladies Rares, FILFOIE, Paris, France No number
6 · The paper itself

Abstract

ABCB11 is responsible for biliary bile acid secretion at the canalicular membrane of hepatocytes. Variations in the

Indexed as

ATP-Binding Cassette TransportersCystic Fibrosis Transmembrane Conductance RegulatorAminophenolsAnimalsCholestasis, IntrahepaticDogsGreen Fluorescent ProteinsQuinolonesTaurocholic AcidAminophenolsATP-Binding Cassette TransportersCystic Fibrosis Transmembrane Conductance RegulatorGreen Fluorescent ProteinsivacaftorQuinolonesTaurocholic AcidABC transporterBSEPcholestasispediatricspotentiatorVX-770

Identifiers

PMID36142670
PMCPMC9502978
OpenAlexW4296281265

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.