Evidence map›Paper›PMID 36142611›Full record

ArticleInternational journal of molecular sciences2022

Anti-Inflammatory Activity of Soluble Epoxide Hydrolase Inhibitors Based on Selenoureas Bearing an Adamantane Moiety.

Vladimir Burmistrov, Christophe Morisseau, Denis A Babkov, Tatiana Golubeva, Dmitry Pitushkin, Elena V Sokolova, Vladimir Vasipov, Yaroslav Kuznetsov, Sergey V Bazhenov, Uliana S Novoyatlova and 7 more

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.5field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 8 institutions in 2 countries.

Vladimir BurmistrovDepartment of Entomology and Nematology, Comprehensive Cancer Center, University of California, Davis, CA 95616, USA.ORCID 0000-0002-8547-9166
Christophe MorisseauDepartment of Entomology and Nematology, Comprehensive Cancer Center, University of California, Davis, CA 95616, USA.ORCID 0000-0002-5672-6631
Denis A BabkovDepartment of Pharmacology & Bioinformatics, Scientific Center for Innovative Drugs, Volgograd State Medical University, 400131 Volgograd, Russia.ORCID 0000-0002-9645-3324
Tatiana GolubevaInstitute of Cytology and Genetics SB RAS, 630090 Novosibirsk, Russia.ORCID 0000-0002-4400-0665
Dmitry PitushkinDepartment of Chemistry, Technology and Equipment of Chemical Industry, Volzhsky Polytechnic Institute (Branch), Volgograd State Technical University, 404121 Volzhsky, Russia.
Elena V SokolovaDepartment of Pharmacology & Bioinformatics, Scientific Center for Innovative Drugs, Volgograd State Medical University, 400131 Volgograd, Russia.
Vladimir VasipovN.I. Vavilov All-Russian Institute of Plant Genetic Resources, 42, 44, Bolshaya Morskaya Street, 190000 St. Petersburg, Russia.
Yaroslav KuznetsovDepartment of Chemistry, Technology and Equipment of Chemical Industry, Volzhsky Polytechnic Institute (Branch), Volgograd State Technical University, 404121 Volzhsky, Russia.
Sergey V BazhenovResearch Center for Molecular Mechanisms of Aging and Age-Related Diseases, Moscow Institute of Physics and Technology, Institutsky Lane 9, 141700 Dolgoprudny, Moscow Region, Russia.
Uliana S NovoyatlovaResearch Center for Molecular Mechanisms of Aging and Age-Related Diseases, Moscow Institute of Physics and Technology, Institutsky Lane 9, 141700 Dolgoprudny, Moscow Region, Russia.
Nikolay A BondarevResearch Center for Molecular Mechanisms of Aging and Age-Related Diseases, Moscow Institute of Physics and Technology, Institutsky Lane 9, 141700 Dolgoprudny, Moscow Region, Russia.ORCID 0000-0001-9230-5546
Ilya V ManukhovResearch Center for Molecular Mechanisms of Aging and Age-Related Diseases, Moscow Institute of Physics and Technology, Institutsky Lane 9, 141700 Dolgoprudny, Moscow Region, Russia.
Victoria OsipovaToxicology Research Group of Southern Scientific Centre of Russian Academy of Science, 41 Chekhova Str., 344006 Rostov-on-Don, Russia.ORCID 0000-0003-2054-4956
Nadezhda BerberovaDepartment of Chemistry, Astrakhan State Technical University, 16 Tatisheva Street, 414056 Astrakhan, Russia.
Alexander A SpasovDepartment of Pharmacology & Bioinformatics, Scientific Center for Innovative Drugs, Volgograd State Medical University, 400131 Volgograd, Russia.ORCID 0000-0002-7185-4826
Gennady M ButovDepartment of Chemistry, Technology and Equipment of Chemical Industry, Volzhsky Polytechnic Institute (Branch), Volgograd State Technical University, 404121 Volzhsky, Russia.
Bruce D HammockDepartment of Entomology and Nematology, Comprehensive Cancer Center, University of California, Davis, CA 95616, USA.ORCID 0000-0003-1408-8317
Moscow Institute of Physics and Technology · RUVolgograd State Technical University · RUVolgograd State Medical University · RUUniversity of California, Davis · USAstrakhan State Technical University · RUN.I. Vavilov Research Institute of Plant Industry · RUNovosibirsk State University · RUSouthern Scientific Center · RU

Funding

Supplement for bioactive lipids as effectors and indicators of the deleterious effects of human healthR35ES030443 · NIEHS · UNIVERSITY OF CALIFORNIA AT DAVIS · PI MORISSEAU, CHRISTOPHE HP · 2019 to 2025
$5.8M
Ministry of Science and Higher Education of the Russian Federation 075-15-2019-1672Ministry of Science and Higher Education of the Russian Federation FWNR-2022-0017NIEHS NIH HHS R35 ES030443Russian Fund for Basic Research 20-03-00298Russian Science Foundation 22-14-00124
6 · The paper itself

Abstract

The inhibitory potency of the series of inhibitors of the soluble epoxide hydrolase (sEH) based on the selenourea moiety and containing adamantane and aromatic lipophilic groups ranges from 34.3 nM to 1.2 μM. The most active compound

Indexed as

AdamantaneEpoxide HydrolasesAnimalsAnti-Inflammatory AgentsEnzyme InhibitorsHumansLipopolysaccharidesMiceNitric OxideOrganoselenium CompoundsUreaAdamantaneAnti-Inflammatory AgentsEnzyme InhibitorsEpoxide HydrolasesLipopolysaccharidesNitric OxideOrganoselenium CompoundsselenoureaUreaadamantaneanti-inflammatoryinhibitorselenoureasoluble epoxide hydrolase

Identifiers

PMID36142611
PMCPMC9501280
OpenAlexW4295927703

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.