Evidence map›Paper›PMID 36142584›Full record

ArticleInternational journal of molecular sciences2022

Silver Nanoparticles Biocomposite Films with Antimicrobial Activity: In Vitro and In Vivo Tests.

Anca Niculina Cadinoiu, Delia Mihaela Rata, Oana Maria Daraba, Daniela Luminita Ichim, Irina Popescu, Carmen Solcan, Gheorghe Solcan

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
3.0field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 41 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
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  6. Review
  7. Recent Developments in Nanoparticle-Hydrogel Hybrid Materials for Controlled Release.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025
    Review
  8. Review
  9. Article
  10. Review
  11. Article
  12. Review
  13. Review
  14. Review
  15. Deploying a Novel Approach to Prepare Silver NanoparticleAntibiotics (Basel, Switzerland) · 2023
    Article
  16. Article
  17. Biopolymer Composites 2022.International journal of molecular sciences · 2023
    Article
  18. PluronicGels (Basel, Switzerland) · 2023
    Article
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Anca Niculina CadinoiuFaculty of Medical Dentistry, "Apollonia" University of Iasi, 700511 Iasi, Romania.ORCID 0000-0002-3708-3992
Delia Mihaela RataFaculty of Medical Dentistry, "Apollonia" University of Iasi, 700511 Iasi, Romania.ORCID 0000-0002-4917-9406
Oana Maria DarabaFaculty of Medical Dentistry, "Apollonia" University of Iasi, 700511 Iasi, Romania.
Daniela Luminita IchimFaculty of Medical Dentistry, "Apollonia" University of Iasi, 700511 Iasi, Romania.
Irina PopescuPetru Poni Institute of Macromolecular Chemistry, 700487 Iasi, Romania.ORCID 0000-0001-6449-8408
Carmen SolcanFaculty of Veterinary Medicine, "Ion Ionescu de la Brad" Iasi University of Life Sciences, 700489 Iasi, Romania.ORCID 0000-0002-0323-0296
Gheorghe SolcanFaculty of Veterinary Medicine, "Ion Ionescu de la Brad" Iasi University of Life Sciences, 700489 Iasi, Romania.ORCID 0000-0002-3067-9574
Apollonia University · RO"Ion Ionescu de la Brad" Iasi University of Life Sciences · ROInstitutul de Chimie Macromoleculară Petru Poni

Funding

Unitatea Executiva Pentru Finantarea Invatamantului Superior a Cercetarii Dezvoltarii si Inovarii PN-III-P2-2.1-PED-2019-1780
6 · The paper itself

Abstract

Overuse of antimicrobials by the population has contributed to genetic modifications in bacteria and development of antimicrobial resistance, which is very difficult to combat nowadays. To solve this problem, it is necessary to develop new systems for the administration of antimicrobial active principles. Biocomposite systems containing silver nanoparticles can be a good medical alternative. In this context, the main objective of this study was to obtain a complex system in the form of a biocomposite film with antimicrobial properties based on chitosan, poly (vinyl alcohol) and silver nanoparticles. This new system was characterized from a structural and morphological point of view. The swelling degree, the mechanical properties and the efficiency of loading and release of an anti-inflammatory drug were also evaluated. The obtained biocomposite films are biocompatibles, this having been demonstrated by in vitro tests on HDFa cell lines, and have antimicrobial activity against

Indexed as

Anti-Infective AgentsChitosanMetal NanoparticlesAnimalsAnti-Bacterial AgentsCyclooxygenase 2HumansPolyvinyl AlcoholRabbitsSilverStaphylococcus aureusAnti-Bacterial AgentsAnti-Infective AgentsChitosanCyclooxygenase 2Polyvinyl AlcoholSilverbiocomposite filmsibuprofensilver nanoparticlesStaphylococcus aureus

Identifiers

PMID36142584
PMCPMC9503464
OpenAlexW4296103529

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.