Evidence map›Paper›PMID 36142569›Full record

ArticleInternational journal of molecular sciences2022

The TGF-β/SMAD Signaling Pathway Prevents Follicular Atresia by Upregulating MORC2.

Jiying Liu, Nannan Qi, Wenwen Xing, Mengxuan Li, Yonghang Qian, Gang Luo, Shali Yu

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.5field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 6 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Jiying LiuSchool of Biotechnology, Jiangsu University of Science and Technology, Zhenjiang 212018, China.
Nannan QiSchool of Biotechnology, Jiangsu University of Science and Technology, Zhenjiang 212018, China.
Wenwen XingSchool of Biotechnology, Jiangsu University of Science and Technology, Zhenjiang 212018, China.
Mengxuan LiSchool of Biotechnology, Jiangsu University of Science and Technology, Zhenjiang 212018, China.
Yonghang QianSchool of Biotechnology, Jiangsu University of Science and Technology, Zhenjiang 212018, China.
Gang LuoSchool of Biotechnology, Jiangsu University of Science and Technology, Zhenjiang 212018, China.ORCID 0000-0002-7821-9243
Shali YuDepartment of Occupational Medicine and Environmental Toxicology, Nantong Key Laboratory of Environmental Toxicology, School of Public Health, Nantong University, Nantong 226019, China.
Jiangsu University of Science and Technology · CNNantong University · CN

Funding

2020_Basic Science Research of Nantong University JC2020042National Natural Science Foundation of China 32102542National Natural Science Foundation of China for Youth 32002175the Natural Science Foundation of Jiangsu Province BK20200994
6 · The paper itself

Abstract

In mammals, female fertility is determined by the outcome of follicular development (ovulation or atresia). The TGF-β/SMAD signaling pathway is an important regulator of this outcome. However, the molecular mechanism by which the TGF-β/SMAD signaling pathway regulates porcine follicular atresia has not been fully elucidated. Microrchidia family CW-type zinc finger 2 (MORC2) is anovel epigenetic regulatory protein widely expressed in plants, nematodes, and mammals. Our previous studies showed that

Indexed as

Follicular AtresiaGranulosa CellsAnimalsFemaleLuciferasesMammalsSignal TransductionSwineTranscription FactorsTransforming Growth Factor betaLuciferasesTranscription FactorsTransforming Growth Factor betafollicular atresiaMORC2porcineTGF-β/SMAD signaling pathway

Identifiers

PMID36142569
PMCPMC9505042
OpenAlexW4296003185

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.