Evidence map›Paper›PMID 36142537›Full record

ArticleInternational journal of molecular sciences2022

Renal Transcriptome and Metabolome in Mice with Principal Cell-Specific Ablation of the Tsc1 Gene: Derangements in Pathways Associated with Cell Metabolism, Growth and Acid Secretion.

Kamyar Zahedi, Sharon Barone, Marybeth Brooks, Tracy Murray Stewart, Robert A Casero, Manoocher Soleimani

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 46% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Role of Extracellular Vesicles in TSC Renal Cystogenesis.International journal of molecular sciences · 2025
    Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Kamyar ZahediDepartment of Internal Medicine, Division of Nephrology, School of Medicine, University of New Mexico, Albuquerque, NM 87131, USA.ORCID 0000-0002-4257-5107
Sharon BaroneDepartment of Internal Medicine, Division of Nephrology, School of Medicine, University of New Mexico, Albuquerque, NM 87131, USA.ORCID 0000-0001-5710-292X
Marybeth BrooksDepartment of Internal Medicine, Division of Nephrology, School of Medicine, University of New Mexico, Albuquerque, NM 87131, USA.
Tracy Murray StewartThe Sidney Kimmel Comprehensive Cancer Center, School of Medicine, Johns Hopkins University, Baltimore, MD 21287, USA.ORCID 0000-0001-8679-6414
Robert A CaseroThe Sidney Kimmel Comprehensive Cancer Center, School of Medicine, Johns Hopkins University, Baltimore, MD 21287, USA.ORCID 0000-0001-5653-3306
Manoocher SoleimaniDepartment of Internal Medicine, Division of Nephrology, School of Medicine, University of New Mexico, Albuquerque, NM 87131, USA.ORCID 0000-0003-4909-4469
University of New Mexico · USJohns Hopkins University · US

Funding

WOMEN'S CANCERS RESEARCH PROGRAMP30CA118100 · NCI · UNIVERSITY OF NEW MEXICO HEALTH SCIS CTR · PI Yolanda Sanchez · 2005 to 2026
$57.1M
Identification of novel spermine oxidase (SMOX) inhibitors as probes for an emerging chemoprevention targetR01CA204345 · NCI · JOHNS HOPKINS UNIVERSITY · PI CASERO, ROBERT A., WOSTER, PATRICK M · 2016 to 2020
$3.4M
The Role of Intercalated Cells and Their Acid Base and Electrolyte Transport Machinery in Kidney Cystogenesis by Tuberous SclerosisI01BX001000 · VA · CINCINNATI VA MEDICAL CENTER RESEARCH · PI SOLEIMANI, MANOOCHER · 2012 to 2025
–
Biomedical Research Institute of New Mexico 372DOpilotgrant\zahediBLRD VA I01 BX001000NCI NIH HHS P30 CA118100NCI NIH HHS R01 CA204345NIH HHS CA-204345United States Department of Veterans Affairs 2 I01 BX001000-10
6 · The paper itself

Abstract

Tuberous sclerosis complex (TSC) is caused by mutations in the hamartin (

Indexed as

Tuberous SclerosisTumor Suppressor ProteinsCreatineGalactoseGTP PhosphohydrolasesGuanosine TriphosphateHumansInosineInositolKidneyMetabolomeNADPhosphatidylinositol 3-KinasesProto-Oncogene Proteins c-aktTranscriptomeTuberous Sclerosis Complex 1 ProteinCreatineGalactoseGTP PhosphohydrolasesGuanosine TriphosphateInosineInositolNADPhosphatidylinositol 3-KinasesProto-Oncogene Proteins c-aktTuberous Sclerosis Complex 1 ProteinTuberous Sclerosis Complex 2 ProteinTumor Suppressor ProteinsUridine Diphosphatecystogenesishamartinkidneymetabolome and transcriptomeprincipal celltuberous sclerosis complex

Identifiers

PMID36142537
PMCPMC9502912
OpenAlexW4296003205

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.