Evidence map›Paper›PMID 36142517›Full record

ArticleInternational journal of molecular sciences2022

Mesenchymal Stem Cells and Formyl Peptide Receptor 2 Activity in Hyperoxia-Induced Lung Injury in Newborn Mice.

Young Eun Kim, So Yoon Ahn, Dong Kyung Sung, Yun Sil Chang, Won Soon Park

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.6field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 4 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Young Eun KimCell and Gene Therapy Institute, Samsung Medical Center, Seoul 06351, Korea.
So Yoon AhnDepartment of Pediatrics, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul 06351, Korea.
Dong Kyung SungDepartment of Pediatrics, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul 06351, Korea.
Yun Sil ChangCell and Gene Therapy Institute, Samsung Medical Center, Seoul 06351, Korea.ORCID 0000-0001-9201-2938
Won Soon ParkCell and Gene Therapy Institute, Samsung Medical Center, Seoul 06351, Korea.
Samsung Medical Center · KR

Funding

Future Medicine 2030 Project from Samsung Medical Center SMX122081Korea Health Industry Development Institute HI14C3484National Research Foundation of Korea NRF-2019R1I1A1A01059951
6 · The paper itself

Abstract

Formyl peptide receptor (FPR) 2 is known to play a critical role in regulating inflammation, including either the pro-inflammatory or pro-resolving effects. However, its role in neonatal hyperoxia-induced lung injury has not been delineated. In this study, we investigate whether mesenchymal stem cells (MSCs) attenuate hyperoxia-induced neonatal lung injury by regulating FPR2 activity. We observed a significant increase in FPR2 levels in alveolar macrophages (RAW264.7 cells) after H

Indexed as

Bronchopulmonary DysplasiaHyperoxiaLung InjuryMesenchymal Stem CellsMesenchymal Stem Cell TransplantationAnimalsAnimals, NewbornCulture Media, ConditionedCytokinesDisease Models, AnimalEndothelial CellsHydrogen PeroxideInflammationLungMiceOxygenCulture Media, ConditionedCytokinesHydrogen PeroxideOxygenReceptors, Formyl PeptideTumor Necrosis Factor-alphabronchopulmonary dysplasiadiseasesformyl peptide receptor 2mesenchymal stem cell transplantationnewborn

Identifiers

PMID36142517
PMCPMC9500980
OpenAlexW4296002955

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.