Evidence map›Paper›PMID 36142504›Full record

ArticleInternational journal of molecular sciences2022

Unveiling the Essential Role of Arkadia's Non-RING Elements in the Ubiquitination Process.

Maria Birkou, Georgia N Delegkou, Konstantinos D Marousis, Nefeli Fragkaki, Tamara Toro, Vasso Episkopou, Georgios A Spyroulias

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.1field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 13 citations in OpenAlex.

  1. Chemical Tools for Probing the Ub/Ubl Conjugation Cascades.Chembiochem : a European journal of chemical biology · 2025
    Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Maria BirkouDepartment of Pharmacy, University of Patras, 26504 Patras, Greece.
Georgia N DelegkouDepartment of Pharmacy, University of Patras, 26504 Patras, Greece.ORCID 0000-0002-0033-9624
Konstantinos D MarousisDepartment of Pharmacy, University of Patras, 26504 Patras, Greece.
Nefeli FragkakiDepartment of Pharmacy, University of Patras, 26504 Patras, Greece.
Tamara ToroDepartment of Pharmacy, University of Patras, 26504 Patras, Greece.ORCID 0000-0003-3295-4231
Vasso EpiskopouDepartment of Brain Sciences, Imperial College, London W12 0NN, UK.
Georgios A SpyrouliasDepartment of Pharmacy, University of Patras, 26504 Patras, Greece.ORCID 0000-0003-1799-3312
University of Patras · GRImperial College London · GB

Funding

Medical Research Council MR/J013331/1Medical Research Council MR/M011194/1
6 · The paper itself

Abstract

Arkadia is a positive regulator of the TGF

Indexed as

IsoleucineUbiquitin-Protein LigasesAlanineArginineAsparagineGlutamineGlycineThreonineTransforming Growth Factor betaUbiquitinUbiquitinationUbiquitin-Conjugating EnzymesAlanineArginineAsparagineGlutamineGlycineIsoleucineThreonineTransforming Growth Factor betaUbiquitinUbiquitin-Conjugating EnzymesUbiquitin-Protein LigasesArkadiaE2 enzymesE3 ligasesnon-RING elements

Identifiers

PMID36142504
PMCPMC9501438
OpenAlexW4296002885

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.