Evidence map›Paper›PMID 36142492›Full record

ArticleInternational journal of molecular sciences2022

Activation of Neutrophils by Mucin-Vaterite Microparticles.

Elena Mikhalchik, Liliya Yu Basyreva, Sergey A Gusev, Oleg M Panasenko, Dmitry V Klinov, Nikolay A Barinov, Olga V Morozova, Alexander P Moscalets, Liliya N Maltseva, Lyubov Yu Filatova and 3 more

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.3field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Redox-Activation of Neutrophils Induced by Pericardium Scaffolds.International journal of molecular sciences · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 4 institutions in 1 country.

Elena MikhalchikFederal Research and Clinical Center of Physical-Chemical Medicine of Federal Medical Biological Agency, 119435 Moscow, Russia.
Liliya Yu BasyrevaFederal Research and Clinical Center of Physical-Chemical Medicine of Federal Medical Biological Agency, 119435 Moscow, Russia.
Sergey A GusevFederal Research and Clinical Center of Physical-Chemical Medicine of Federal Medical Biological Agency, 119435 Moscow, Russia.ORCID 0000-0003-0383-2649
Oleg M PanasenkoFederal Research and Clinical Center of Physical-Chemical Medicine of Federal Medical Biological Agency, 119435 Moscow, Russia.ORCID 0000-0001-5245-2285
Dmitry V KlinovFederal Research and Clinical Center of Physical-Chemical Medicine of Federal Medical Biological Agency, 119435 Moscow, Russia.
Nikolay A BarinovFederal Research and Clinical Center of Physical-Chemical Medicine of Federal Medical Biological Agency, 119435 Moscow, Russia.
Olga V MorozovaFederal Research and Clinical Center of Physical-Chemical Medicine of Federal Medical Biological Agency, 119435 Moscow, Russia.ORCID 0000-0001-9630-0777
Alexander P MoscaletsFederal Research and Clinical Center of Physical-Chemical Medicine of Federal Medical Biological Agency, 119435 Moscow, Russia.
Liliya N MaltsevaFaculty of Chemistry, Lomonosov Moscow State University, 119991 Moscow, Russia.ORCID 0000-0001-9003-6098
Lyubov Yu FilatovaFaculty of Chemistry, Lomonosov Moscow State University, 119991 Moscow, Russia.
Evgeniy A PronkinFederal Research and Clinical Center of Physical-Chemical Medicine of Federal Medical Biological Agency, 119435 Moscow, Russia.ORCID 0000-0001-9011-2150
Julia A BespyatykhFederal Research and Clinical Center of Physical-Chemical Medicine of Federal Medical Biological Agency, 119435 Moscow, Russia.ORCID 0000-0002-4408-503X
Nadezhda G BalabushevichFaculty of Chemistry, Lomonosov Moscow State University, 119991 Moscow, Russia.
Federal Medical-Biological Agency · RULomonosov Moscow State University · RUSirius University of Science and Technology · RUD. Mendeleyev University of Chemical Technology of Russia · RU

Funding

Development Program of Lomonosov MSU and registration theme 121041500039-8Russian Science Foundation 20-1500390
6 · The paper itself

Abstract

Nano- and microparticles enter the body through the respiratory airways and the digestive system, or form as biominerals in the gall bladder, salivary glands, urinary bladder, kidney, or diabetic pancreas. Calcium, magnesium, and phosphate ions can precipitate from biological fluids in the presence of mucin as hybrid nanoparticles. Calcium carbonate nanocrystallites also trap mucin and are assembled into hybrid microparticles. Both mucin and calcium carbonate polymorphs (calcite, aragonite, and vaterite) are known to be components of such biominerals as gallstones which provoke inflammatory reactions. Our study was aimed at evaluation of neutrophil activation by hybrid vaterite-mucin microparticles (CCM). Vaterite microparticles (CC) and CCM were prepared under standard conditions. The diameter of CC and CCM was 3.3 ± 0.8 µm and 5.8 ± 0.7 µm, with ƺ-potentials of -1 ± 1 mV and -7 ± 1 mV, respectively. CC microparticles injured less than 2% of erythrocytes in 2 h at 1.5 mg mL

Indexed as

LuminolNeutrophilsCalciumCalcium CarbonateCalcium OxalateInterleukin-10Interleukin-6Interleukin-8IonsMagnesiumMucinsOxidantsPhosphatesTumor Necrosis Factor-alphaZymosanCalciumCalcium CarbonateCalcium OxalateInterleukin-10Interleukin-6Interleukin-8IonsLuminolMagnesiumMucinsOxidantsPhosphatesTumor Necrosis Factor-alphaZymosanchemiluminescencecytokinesinflammationmicroparticlesmucinneutrophilsvaterite

Identifiers

PMID36142492
PMCPMC9501559
OpenAlexW4295846852

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.