ReviewInternational journal of molecular sciences2022
The Rheology and Physicochemical Characteristics of Hyaluronic Acid Fillers: Their Clinical Implications.
Review in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 76 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
76 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Clinical Durability of Hyaluronic Acid-Based Dermal Fillers for Facial Application: A Systematic Review.Aesthetic plastic surgery · 2026Pooled it
- A Comparative Study of the Efficacy of Different Tissue Fillers for Nasolabial Fold Correction.Aesthetic plastic surgery · 2026Pooled it
- Conditions to Consider When Choosing Fillers.Journal of cosmetic dermatology · 2025Pooled it
- Efficacy and Safety of Chin Augmentation Using MaiLi-E, a Lidocaine-Containing Cross-Linked Sodium Hyaluronate Gel.Aesthetic plastic surgery · 2025Trial
- Evaluating the Efficacy of Acupotomy Subcision and Hyaluronic Acid Injections for Neck Wrinkles: A Randomized Trial.Journal of cosmetic dermatology · 2025Trial
- Comparative Trial Evaluating a High- Versus Low-Integration Hyaluronic Acid Filler for Contouring the Jawline.Aesthetic plastic surgery · 2025Trial
- Efficacy and Safety of Non-Cross-Linked Sodium Hyaluronate Composite Solution Injection for Skin Condition Improvement: A Prospective, Multicenter, Randomized, Evaluator-Blinded, Blank-Controlled Superiority Trial.Aesthetic plastic surgery · 2026Article
- Beyond reconstruction: minimally invasive aesthetic and regenerative medicine in postoperative oral and maxillofacial surgery.Oral and maxillofacial surgery · 2026Review
- Malar Edema after Hyaluronic Acid Dermal Fillers: Expert Recommendations on Etiology, Prevention, and Management.Dermatology and therapy · 2026Review
- Non-Surgical Ear Rejuvenation Through Selective Neuromodulation with Onabotulinum and Abobotulinum Toxin-A.Toxins · 2026Article
- The PATH Protocol for Integrated Facial Rejuvenation: A Preliminary Three-Patient Case Report Series and Narrative Review of the Literature.Reports (MDPI) · 2026Article
- Review
- Effects of Intra-Articular Administration of High-Molecular-Weight Linear Hyaluronic Acid on Synovial Fluid Characteristics and Joint Environment.Antioxidants (Basel, Switzerland) · 2026Article
- iLipsAesthetic plastic surgery · 2026Article
- Performance and Safety of Hyaluronic Acid-Based Gynaecological Filler for Labia Majora Augmentation: A Randomised Controlled Study.Life (Basel, Switzerland) · 2026Article
- Ultrasound Evaluation of Lip Anatomy and Filler Placement: A Cross-Sectional Study of Injection Accuracy, Migration, and Demographic Variation.Plastic and reconstructive surgery · 2026Article
- Debunking Myths on Hyaluronic Acid Injectable Gels in Clinical Practice.Plastic and reconstructive surgery. Global open · 2026Article
- Review
- Hyaluronidase Reverses the Effect of Hyaluronic Acid Without Destroying Normal Skin Structure.Journal of cosmetic dermatology · 2026Article
- 3D Bioprinting of Blood Vessel Model for Improving Wound Healing.International journal of molecular sciences · 2026Article
16 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
Abstract
Hyaluronic acid (HA) fillers have become the most popular material for facial volume augmentation and wrinkle correction. Several filler brands are currently on the market all around the world and their features are extremely variable; for this reason, most users are unaware of their differences. The study of filler rheology has become a wellspring of knowledge, differentiating HA fillers, although these properties are not described thoroughly by the manufacturers. The authors of this review describe the more useful rheological properties that can help clinicians understand filler characteristics and the likely correlation of these features with clinical outcomes.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.