Evidence map›Paper›PMID 36142427›Full record

ArticleInternational journal of molecular sciences2022

Addition of Synthetic Biomaterials to Deproteinized Bovine Bone Mineral (DBBM) for Bone Augmentation-A Preclinical In Vivo Study.

Masako Fujioka-Kobayashi, Hiroki Katagiri, Niklaus P Lang, Jean-Claude Imber, Benoit Schaller, Nikola Saulacic

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.4field-weighted citation impact, top 45% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 2 countries.

Masako Fujioka-KobayashiDepartment of Cranio-Maxillofacial Surgery, University Hospital, University of Bern, 3010 Bern, Switzerland.
Hiroki KatagiriDepartment of Cranio-Maxillofacial Surgery, University Hospital, University of Bern, 3010 Bern, Switzerland.ORCID 0000-0002-7464-3274
Niklaus P LangDepartment of Cranio-Maxillofacial Surgery, University Hospital, University of Bern, 3010 Bern, Switzerland.
Jean-Claude ImberDepartment of Periodontology, School of Dental Medicine, University of Bern, 3010 Bern, Switzerland.ORCID 0000-0001-6690-5249
Benoit SchallerDepartment of Cranio-Maxillofacial Surgery, University Hospital, University of Bern, 3010 Bern, Switzerland.ORCID 0000-0002-6861-2340
Nikola SaulacicDepartment of Cranio-Maxillofacial Surgery, University Hospital, University of Bern, 3010 Bern, Switzerland.ORCID 0000-0003-3960-4920
University of Bern · CH

Funding

Geistlich Pharma AG 400130
6 · The paper itself

Abstract

(1) Aim: To investigate the effect of synthetic bone substitutes, α-tricalcium phosphate (α-TCP) or bi-layered biphasic calcium-phosphate (BBCP) combined with deproteinized bovine bone mineral (DBBM), on bone formation. (2) Methods: Thirty critical size defects were randomly treated with the following five different treatment modalities: (1) negative control (NC, empty), (2) DBBM, (3) α-TCP + DBBM (1:1), (4) BBCP 3%HA/97%α-TCP + DBBM (1:1), and (5) BBCP 6%HA/94%α-TCP + DBBM (1:1). The samples, at four weeks post-surgery, were investigated by micro-CT and histological analysis. (3) Results: A similar level of new bone formation was demonstrated in the DBBM with α-TCP bone substitute groups when compared to the negative control by histomorphometry. DBBM alone showed significantly lower new bone area than the negative control (

Indexed as

Bone SubstitutesAnimalsBiocompatible MaterialsBiological ProductsBone RegenerationCalciumCalcium PhosphatesCattleHydroxyapatitesMineralsalpha-tricalcium phosphateBiocompatible MaterialsBiological Productsbone mealBone SubstitutesCalciumCalcium Phosphateshydroxyapatite-beta tricalcium phosphateHydroxyapatitesMineralsbiomaterialsbiphasic calcium phosphatebone augmentationin vivotricalcium phosphate

Identifiers

PMID36142427
PMCPMC9505841
OpenAlexW4296810522

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.