Evidence map›Paper›PMID 36142415›Full record

ArticleInternational journal of molecular sciences2022

Valorization of Biomasses from Energy Crops for the Discovery of Novel Thermophilic Glycoside Hydrolases through Metagenomic Analysis.

Roberta Iacono, Andrea Strazzulli, Rosa Giglio, Federica Bitetti, Beatrice Cobucci-Ponzano, Marco Moracci

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
2.3field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
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  5. Extremophiles in a changing world.Extremophiles : life under extreme conditions · 2024
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Roberta IaconoDepartment of Biology, University of Naples "Federico II", Complesso Universitario di Monte S. Angelo, Via Cupa Nuova Cinthia 21, 80126 Naples, Italy.ORCID 0000-0002-3586-4322
Andrea StrazzulliDepartment of Biology, University of Naples "Federico II", Complesso Universitario di Monte S. Angelo, Via Cupa Nuova Cinthia 21, 80126 Naples, Italy.ORCID 0000-0002-9690-149X
Rosa GiglioInstitute of Biosciences and BioResources-National Research Council of Italy, Via P. Castellino 111, 80131 Naples, Italy.ORCID 0000-0002-3062-3933
Federica BitettiInstitute of Biosciences and BioResources-National Research Council of Italy, Via P. Castellino 111, 80131 Naples, Italy.
Beatrice Cobucci-PonzanoInstitute of Biosciences and BioResources-National Research Council of Italy, Via P. Castellino 111, 80131 Naples, Italy.ORCID 0000-0002-8211-2297
Marco MoracciDepartment of Biology, University of Naples "Federico II", Complesso Universitario di Monte S. Angelo, Via Cupa Nuova Cinthia 21, 80126 Naples, Italy.ORCID 0000-0002-9846-2531
Institute of Biosciences and Bioresources · ITUniversity of Naples Federico II · IT

Funding

Ministero dell'Università e della Ricerca Scentifica PON01 01966, funded in the frame of Operative National Programme Research and Competi-tiveness 2007-2013 D. D. Prot. n. 01/Ric. 18.1.2010
6 · The paper itself

Abstract

The increasing interest for environmentally friendly technologies is driving the transition from fossil-based economy to bioeconomy. A key enabler for circular bioeconomy is to valorize renewable biomasses as feedstock to extract high value-added chemicals. Within this transition the discovery and the use of robust biocatalysts to replace toxic chemical catalysts play a significant role as technology drivers. To meet both the demands, we performed microbial enrichments on two energy crops, used as low-cost feed for extremophilic consortia. A culture-dependent approach coupled to metagenomic analysis led to the discovery of more than 300 glycoside hydrolases and to characterize a new α-glucosidase from an unknown hyperthermophilic archaeon. Aglu1 demonstrated to be the most active archaeal GH31 on 4Np-α-Glc and it showed unexpected specificity vs. kojibiose, revealing to be a promising candidate for biotechnological applications such as the liquefaction/saccharification of starch.

Indexed as

alpha-GlucosidasesGlycoside HydrolasesArchaeaBiomassCrops, AgriculturalMetagenomicsStarchalpha-GlucosidasesGlycoside HydrolasesStarcharchaeaCAZymesenrichmentsextremozymes

Identifiers

PMID36142415
PMCPMC9505709
OpenAlexW4296003206

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.