Evidence map›Paper›PMID 36142383›Full record

ArticleInternational journal of molecular sciences2022

Potent Chlorambucil-Platinum(IV) Prodrugs.

Angelico D Aputen, Maria George Elias, Jayne Gilbert, Jennette A Sakoff, Christopher P Gordon, Kieran F Scott, Janice R Aldrich-Wright

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
2.0field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 19 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Angelico D AputenSchool of Science, Western Sydney University, Locked Bag 1797, Penrith South DC, Sydney, NSW 2751, Australia.
Maria George EliasSchool of Science, Western Sydney University, Locked Bag 1797, Penrith South DC, Sydney, NSW 2751, Australia.
Jayne GilbertCalvary Mater Hospital, Waratah, NSW 2298, Australia.
Jennette A SakoffCalvary Mater Hospital, Waratah, NSW 2298, Australia.
Christopher P GordonSchool of Science, Western Sydney University, Locked Bag 1797, Penrith South DC, Sydney, NSW 2751, Australia.
Kieran F ScottIngham Institute, Liverpool, NSW 2170, Australia.ORCID 0000-0002-6012-4107
Janice R Aldrich-WrightSchool of Science, Western Sydney University, Locked Bag 1797, Penrith South DC, Sydney, NSW 2751, Australia.ORCID 0000-0002-6943-6908
Western Sydney University · AUCalvary Mater Newcastle Hospital · AUIngham Institute · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The DNA-alkylating derivative chlorambucil was coordinated in the axial position to atypical cytotoxic, heterocyclic, and non-DNA coordinating platinum(IV) complexes of type,

Indexed as

Antineoplastic AgentsOvarian NeoplasmsProdrugsCarboplatinCell Line, TumorChlorambucilCisplatinFemaleHumansMaleOrganoplatinum CompoundsOxaliplatinPlatinumReactive Oxygen SpeciesAntineoplastic AgentsCarboplatinChlorambucilCisplatinOrganoplatinum CompoundsOxaliplatinPlatinumProdrugsReactive Oxygen Species56MESS5MESSchlorambucilcytotoxicityDNAPHENSSplatinum(II)platinum(IV)ROS

Identifiers

PMID36142383
PMCPMC9499463
OpenAlexW4296003121

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.