Evidence map›Paper›PMID 36142353›Full record

ReviewInternational journal of molecular sciences2022

CRISPR/Cas9 Technology and Its Utility for Crop Improvement.

Hua Liu, Wendan Chen, Yushu Li, Lei Sun, Yuhong Chai, Haixia Chen, Haochen Nie, Conglin Huang

Open access · goldAbstract readReview
In one paragraph

Review in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
5.5field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 66 citations in OpenAlex.

  1. Article
  2. Review
  3. Wheat's Up with CRISPR-Cas-Current Advances, Obstacles and Perspectives.International journal of molecular sciences · 2026
    Review
  4. Review
  5. A NovelPlants (Basel, Switzerland) · 2026
    Article
  6. Review
  7. Review
  8. Article
  9. Article
  10. Article
  11. BES-Designer: A Web Tool to Design Guide RNAs for Base Editing to Simplify Library.Interdisciplinary sciences, computational life sciences · 2025
    Article
  12. Review
  13. Review
  14. Article
  15. Article
  16. Review
  17. Review
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Hua LiuBeijing Academy of Agriculture and Forestry Sciences, Beijing 100097, China.
Wendan ChenBeijing Key Laboratory of Forest Food Processing and Safety, Department of Food Science and Engineering, College of Biological Sciences and Biotechnology, Beijing Forestry University, Beijing 100083, China.
Yushu LiBeijing Vocational College of Agriculture, Beijing 100097, China.
Lei SunBeijing Academy of Agriculture and Forestry Sciences, Beijing 100097, China.ORCID 0000-0003-1695-6480
Yuhong ChaiBeijing Academy of Agriculture and Forestry Sciences, Beijing 100097, China.
Haixia ChenBeijing Academy of Agriculture and Forestry Sciences, Beijing 100097, China.
Haochen NieBeijing Academy of Agriculture and Forestry Sciences, Beijing 100097, China.
Conglin HuangBeijing Academy of Agriculture and Forestry Sciences, Beijing 100097, China.
Beijing Academy of Agricultural and Forestry Sciences · CNBeijing Forestry University · CNBeijing Health Vocational College · CN

Funding

State Natural Science Funds Commission,Study on breeding technology and ecological adaptability of Lily for both ornament and food ,Innovation Foundation of the Beijing 698 Academy of Agriculture and Forestry Sciences 31901354,KM202112448004,KJCX20200112
6 · The paper itself

Abstract

The rapid growth of the global population has resulted in a considerable increase in the demand for food crops. However, traditional crop breeding methods will not be able to satisfy the worldwide demand for food in the future. New gene-editing technologies, the most widely used of which is CRISPR/Cas9, may enable the rapid improvement of crop traits. Specifically, CRISPR/Cas9 genome-editing technology involves the use of a guide RNA and a Cas9 protein that can cleave the genome at specific loci. Due to its simplicity and efficiency, the CRISPR/Cas9 system has rapidly become the most widely used tool for editing animal and plant genomes. It is ideal for modifying the traits of many plants, including food crops, and for creating new germplasm materials. In this review, the development of the CRISPR/Cas9 system, the underlying mechanism, and examples of its use for editing genes in important crops are discussed. Furthermore, certain limitations of the CRISPR/Cas9 system and potential solutions are described. This article will provide researchers with important information regarding the use of CRISPR/Cas9 gene-editing technology for crop improvement, plant breeding, and gene functional analyses.

Indexed as

CRISPR-Associated Protein 9CRISPR-Cas SystemsAnimalsCrops, AgriculturalGene EditingGenome, PlantPlant BreedingRNA, Guide, CRISPR-Cas SystemsTechnologyCRISPR-Associated Protein 9RNA, Guide, CRISPR-Cas SystemsCRISPR/Cas9crop improvementgene editinggene functionplant breeding

Identifiers

PMID36142353
PMCPMC9499353
OpenAlexW4296793846

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.