Evidence map›Paper›PMID 36142336›Full record

Observational studyInternational journal of molecular sciences2022

Inflammatory Biomarkers Associated with In-Hospital Mortality in Critical COVID-19 Patients.

Krisztina Pál, Anca Alexandra Molnar, Adina Huțanu, János Szederjesi, Ionuț Branea, Ágota Timár, Minodora Dobreanu

Abstract readObservational Study
In one paragraph

Observational study in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Article
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  5. Antibiotics (Basel, Switzerland) · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Krisztina PálDepartment of Laboratory Medicine, Emergency Clinical County Hospital, 540136 Targu Mures, Romania.
Anca Alexandra MolnarDepartment of Laboratory Medicine, Emergency Clinical County Hospital, 540136 Targu Mures, Romania.
Adina HuțanuDepartment of Laboratory Medicine, Emergency Clinical County Hospital, 540136 Targu Mures, Romania.ORCID 0000-0001-9798-1594
János SzederjesiDepartment of Anesthesiology and Intensive Care, George Emil Palade University of Medicine, Pharmacy, Science, and Technology of Targu Mures, 540142 Targu Mures, Romania.
Ionuț BraneaDepartment of Anesthesiology and Intensive Care, Emergency Clinical County Hospital, 540136 Targu Mures, Romania.ORCID 0000-0003-4732-6078
Ágota TimárDepartment of Anesthesiology and Intensive Care, George Emil Palade University of Medicine, Pharmacy, Science, and Technology of Targu Mures, 540142 Targu Mures, Romania.
Minodora DobreanuDepartment of Laboratory Medicine, Emergency Clinical County Hospital, 540136 Targu Mures, Romania.ORCID 0000-0003-3214-3631

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The COVID-19 pandemic poses global healthcare challenges due to its unpredictable clinical course. The aim of this study is to identify inflammatory biomarkers and other routine laboratory parameters associated with in-hospital mortality in critical COVID-19 patients. We performed a retrospective observational study on 117 critical COVID-19 patients. Following descriptive statistical analysis of the survivor and non-survivor groups, optimal cut-off levels for the statistically significant parameters were determined using the ROC method, and the corresponding Kaplan-Meier survival curves were calculated. The inflammatory parameters that present statistically significant differences between survivors and non-survivors are IL-6 (

Indexed as

COVID-19BiomarkersCreatinineHospital MortalityHumansInterleukin-6PandemicsRetrospective StudiesROC CurveUreaBiomarkersCreatinineInterleukin-6UreaCOVID-19IL-6inflammation

Identifiers

PMID36142336
PMCPMC9499352

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.