Evidence map›Paper›PMID 36142330›Full record

ArticleInternational journal of molecular sciences2022

Innate Immune Response Analysis in Meniscus Xenotransplantation Using Normal and Triple Knockout Jeju Native Pigs.

Seungwon Yoon, Yunhui Min, Chungyu Park, Dahye Kim, Yunji Heo, Mangeun Kim, Eugene Son, Mrinmoy Ghosh, Young-Ok Son, Chang-Gi Hur

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.3field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
  3. Transplant Immunobiology: Many Answers Raising Even More Questions.International journal of molecular sciences · 2023
    Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 2 countries.

Seungwon YoonCronex Co., Jeju-si 63078, Korea.
Yunhui MinInterdisciplinary Graduate Program in Advanced Convergence Technology and Science, Jeju National University, Jeju-si 63243, Korea.
Chungyu ParkCronex Co., Jeju-si 63078, Korea.
Dahye KimDivision of Animal Genetics and Bioinformatics, The National Institute of Animal Science, RDA, Wanju 55465, Korea.
Yunji HeoDepartment of Animal Biotechnology, Faculty of Biotechnology, College of Applied Life Sciences, Jeju National University, Jeju-si 63243, Korea.
Mangeun KimInterdisciplinary Graduate Program in Advanced Convergence Technology and Science, Jeju National University, Jeju-si 63243, Korea.
Eugene SonCronex Inc., Hwaseong 18525, Korea.
Mrinmoy GhoshDepartment of Animal Biotechnology, Faculty of Biotechnology, College of Applied Life Sciences, Jeju National University, Jeju-si 63243, Korea.ORCID 0000-0001-6817-622X
Young-Ok SonInterdisciplinary Graduate Program in Advanced Convergence Technology and Science, Jeju National University, Jeju-si 63243, Korea.ORCID 0000-0003-0154-4061
Chang-Gi HurCronex Co., Jeju-si 63078, Korea.ORCID 0000-0003-4526-3886
Jeju National University · KRNational Institute of Animal Science · KR

Funding

ICT Development R&D Program of MSIT 2020R1A2C2004128Korea Basic Science Institute 2020R1A6C101A188Technology Development Program of MSS S3248847
6 · The paper itself

Abstract

Although allogenic meniscus grafting can be immunologically safe, it causes immune rejection due to an imbalanced tissue supply between donor and recipient. Pigs are anatomically and physiologically similar to adult humans and are, therefore, considered to be advantageous xenotransplantation models. However, immune rejection caused by genetic difference damages the donor tissue and can sometimes cause sudden death. Immune rejection is caused by genes; porcine

Indexed as

Immunity, InnateMeniscusAnimalsAnimals, Genetically ModifiedCytokinesEpitopesGalactosyltransferasesGene Knockout TechniquesGraft RejectionHumansMiceMice, KnockoutSwineTransplantation, HeterologousCytokinesEpitopesGalactosyltransferasesimmune rejectionmeniscustriple knockoutxenotransplantation

Identifiers

PMID36142330
PMCPMC9499368
OpenAlexW4295094843

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.