ReviewInternational journal of molecular sciences2022
Applications of Metabolomics in Calcium Metabolism Disorders in Humans.
Review in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed, 14 citations in OpenAlex.
- The intrinsic link between the double burden of dental caries and stunting in children: the gut microbiota plays a key role.BMC microbiology · 2026Article
- Study of the early metabolic characteristics in patients undergoing sleeve gastrectomy for the treatment of obesity and type 2 diabetes mellitus (T2DM) using high-performance liquid chromatography combined with high-resolution mass spectrometry via metabolomics technology.Archives of endocrinology and metabolism · 2025Article
- Impact of subclinically hypocalcemic stress on the plasma metabolomic profile of dairy goats.Animal bioscience · 2025Article
- Combining untargeted and targeted metabolomic profiling reveals principal differences between osteopenia, Osteoporosis and healthy controls.Aging clinical and experimental research · 2025Article
- Metabolic perturbations in cardiomyopathies: implications for early diagnosis and targeted interventions.Frontiers in cardiovascular medicine · 2025Review
- New insight into primary hyperparathyroidism using untargeted metabolomics.Scientific reports · 2024Article
- Metabolomic profile of secondary hyperparathyroidism in patients with chronic kidney disease stages 3-5 not receiving dialysis.Frontiers in endocrinology · 2024Article
- Effects of Menaquinone-7 on the Bone Health of Growing Rats under Calcium Restriction: New Insights from Microbiome-Metabolomics.Nutrients · 2023Article
- Metabolism of parathyroid organoids.Frontiers in endocrinology · 2023Article
- Fighting Obesity-Related Micronutrient Deficiencies through Biofortification of Agri-Food Crops with Sustainable Fertilization Practices.Plants (Basel, Switzerland) · 2022Review
- Application of metabolomics in osteoporosis research.Frontiers in endocrinology · 2022Review
Corrections and comments
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Authors and funding
8 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The pathogenesis of the disorders of calcium metabolism is not fully understood. This review discusses the studies in which metabolomics was applied in this area. Indeed, metabolomics could play an essential role in discovering biomarkers and elucidating pathological mechanisms. Despite the limited bibliography, the present review highlights the potential of metabolomics in identifying the biomarkers of some of the most common endocrine disorders, such as primary hyperparathyroidism (PHPT), secondary hyperparathyroidism (SHPT), calcium deficiency, osteoporosis and vitamin D supplementation. Metabolites related to above-mentioned diseorders were grouped into specific classes and mapped into metabolic pathways. Furthermore, disturbed metabolic pathways can open up new directions for the in-depth exploration of the basic mechanisms of these diseases at the molecular level.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.