Evidence map›Paper›PMID 36142293›Full record

ArticleInternational journal of molecular sciences2022

Stereoselective Synthesis and Application of Gibberellic Acid-Derived Aminodiols.

Zein Alabdeen Khdar, Tam Minh Le, Zsuzsanna Schelz, István Zupkó, Zsolt Szakonyi

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Stereoselective Synthesis and Antimicrobial Studies ofPharmaceuticals (Basel, Switzerland) · 2025
    Article
  3. Gibberellic Acid (GAChemistry & biodiversity · 2025
    Review
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Zein Alabdeen KhdarInstitute of Pharmaceutical Chemistry, University of Szeged, Interdisciplinary Excellent Center, Eötvös utca 6, H-6720 Szeged, Hungary.
Tam Minh LeInstitute of Pharmaceutical Chemistry, University of Szeged, Interdisciplinary Excellent Center, Eötvös utca 6, H-6720 Szeged, Hungary.ORCID 0000-0002-8296-887X
Zsuzsanna SchelzInstitute of Pharmacodynamics and Biopharmacy, University of Szeged, Interdisciplinary Excellent Center, H-6720 Szeged, Hungary.ORCID 0000-0002-8519-4830
István ZupkóInstitute of Pharmacodynamics and Biopharmacy, University of Szeged, Interdisciplinary Excellent Center, H-6720 Szeged, Hungary.ORCID 0000-0003-3243-5300
Zsolt SzakonyiInstitute of Pharmaceutical Chemistry, University of Szeged, Interdisciplinary Excellent Center, Eötvös utca 6, H-6720 Szeged, Hungary.ORCID 0000-0003-2432-8409

Funding

Ministry of Human Capacities TKP2021-EGA-32National Research, Development and Innovation Fund TKP2021-EGANational Research, Development and Innovation Office K138871
6 · The paper itself

Abstract

A series of gibberellic acid-based aminodiols was designed and synthesized from commercially available gibberellic acid. Exposure of gibberellic acid to hydrochloric acid under reflux conditions resulted in aromatization followed by rearrangement to form allo-gibberic acid. The key intermediate, ethyl allo-gibberate, was prepared according to literature methods. Epoxidation of key intermediate and subsequent ring-opening of the corresponding epoxide with different nucleophiles resulted in

Indexed as

Antineoplastic AgentsNeoplasmsEpoxy CompoundsFormaldehydeGibberellinsHumansHydrochloric AcidMolecular StructureNitrogenStructure-Activity RelationshipAntineoplastic AgentsEpoxy CompoundsFormaldehydegibberellic acidGibberellinsHydrochloric AcidNitrogen3-amino-1,2-diolsallo-gibberic acidantiproliferative activityditerpenegibberellic acid

Identifiers

PMID36142293
PMCPMC9499365

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.