Evidence map›Paper›PMID 36142252›Full record

ArticleInternational journal of molecular sciences2022

Different Inhibition of Nrf2 by Two Keap1 Isoforms α and β to Shape Malignant Behaviour of Human Hepatocellular Carcinoma.

Feilong Chen, Mei Xiao, Jing Feng, Reziyamu Wufur, Keli Liu, Shaofan Hu, Yiguo Zhang

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.0field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Article
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  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. NOP16 promotes hepatocellular carcinoma progression and triggers EMT through the Keap1-Nrf2 signaling pathway.Technology and health care : official journal of the European Society for Engineering and Medicine · 2024
    Article
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Feilong ChenCollege of Bioengineering, Graduate School, Chongqing University, No. 174 Shazheng Street, Shapingba District, Chongqing 400044, China.
Mei XiaoCollege of Bioengineering, Graduate School, Chongqing University, No. 174 Shazheng Street, Shapingba District, Chongqing 400044, China.
Jing FengCollege of Bioengineering, Graduate School, Chongqing University, No. 174 Shazheng Street, Shapingba District, Chongqing 400044, China.
Reziyamu WufurCollege of Bioengineering, Graduate School, Chongqing University, No. 174 Shazheng Street, Shapingba District, Chongqing 400044, China.ORCID 0000-0002-5151-9289
Keli LiuCollege of Bioengineering, Graduate School, Chongqing University, No. 174 Shazheng Street, Shapingba District, Chongqing 400044, China.
Shaofan HuCollege of Bioengineering, Graduate School, Chongqing University, No. 174 Shazheng Street, Shapingba District, Chongqing 400044, China.
Yiguo ZhangChongqing University Jiangjin Hospital, School of Medicine, Chongqing University, No. 725 Jiangzhou Avenue, Dingshan Street, Jiangjin District, Chongqing 402260, China.ORCID 0000-0003-3910-2779
Chongqing University · CN

Funding

the National Natural Science Foundation of China 81872336the National Natural Science Foundation of China 82073079the National Natural Science Foundation of China 91429305
6 · The paper itself

Abstract

Nrf2 (nuclear factor E2-related factor 2, encoded by

Indexed as

Carcinoma, HepatocellularLiver NeoplasmsNF-E2-Related Factor 2AnimalsAntioxidantsHumansKelch-Like ECH-Associated Protein 1MiceMice, NudeOxidative StressPhosphatidylinositol 3-KinasesProtein IsoformsProto-Oncogene Proteins c-aktTOR Serine-Threonine KinasesAntioxidantsKEAP1 protein, humanKeap1 protein, mouseKelch-Like ECH-Associated Protein 1NFE2L2 protein, humanNF-E2-Related Factor 2Phosphatidylinositol 3-KinasesProtein IsoformsProto-Oncogene Proteins c-aktTOR Serine-Threonine KinasesEMTHO-1Keap1Keap1αKeap1βmTORNrf2PI3KPTEN

Identifiers

PMID36142252
PMCPMC9499251
OpenAlexW4294934860

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.