Evidence map›Paper›PMID 36142236›Full record

ArticleInternational journal of molecular sciences2022

Isoquinoline Alkaloids from

Sylwia Nakonieczna, Aneta Grabarska, Kinga Gawel, Paula Wróblewska-Łuczka, Arkadiusz Czerwonka, Andrzej Stepulak, Wirginia Kukula-Koch

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. The Search for Drugs Derived from Natural Products forCurrent topics in medicinal chemistry · 2024
    Pooled it
  2. Advancements in Zebrafish Models for Breast Cancer Research: Unveiling Biomarkers, Targeted Therapies, and Personalized Medicine.Medical science monitor : international medical journal of experimental and clinical research · 2023
    Pooled it
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
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  10. Current pharmaceutical design · 2026
    Article
  11. Article
  12. Review
  13. Article
  14. Article
  15. Article
  16. Review
  17. Review
  18. Article
  19. Current topics in medicinal chemistry · 2024
    Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Sylwia NakoniecznaDepartment of Pharmacognosy with Medicinal Plants Garden, Medical University of Lublin, 1 Chodzki Str., 20-093 Lublin, Poland.
Aneta GrabarskaDepartment of Biochemistry and Molecular Biology, Medical University of Lublin, 1 Chodzki Str., 20-093 Lublin, Poland.ORCID 0000-0002-3823-1467
Kinga GawelDepartment of Experimental and Clinical Pharmacology, Medical University of Lublin, 8b Jaczewskiego Str., 20-090 Lublin, Poland.ORCID 0000-0001-8857-847X
Paula Wróblewska-ŁuczkaDepartment of Pathophysiology, Medical University of Lublin, 8b Jaczewskiego Str., 20-090 Lublin, Poland.ORCID 0000-0002-7099-1968
Arkadiusz CzerwonkaDepartment of Biochemistry and Molecular Biology, Medical University of Lublin, 1 Chodzki Str., 20-093 Lublin, Poland.
Andrzej StepulakDepartment of Biochemistry and Molecular Biology, Medical University of Lublin, 1 Chodzki Str., 20-093 Lublin, Poland.ORCID 0000-0002-1872-394X
Wirginia Kukula-KochDepartment of Pharmacognosy with Medicinal Plants Garden, Medical University of Lublin, 1 Chodzki Str., 20-093 Lublin, Poland.ORCID 0000-0001-7076-600X

Funding

Medical University of Lublin DS 24Medical University of Lublin DS 440Medical University of Lublin DS 448
6 · The paper itself

Abstract

Gastric cancer (GC) has high incidence rates and constitutes a common cause of cancer mortality. Despite advances in treatment, GC remains a challenge in cancer therapy which is why novel treatment strategies are needed. The interest in natural compounds has increased significantly in recent years because of their numerous biological activities, including anti-cancer action. The isolation of the bioactive compounds from

Indexed as

AlkaloidsBerberineBerberine AlkaloidsCoptisDrugs, Chinese HerbalStomach NeoplasmsAnimalsBromodeoxyuridineChloroformCisplatinCoptis chinensisHydrochloric AcidIsoquinolinesMethanolSolventsWaterAlkaloidsBerberineBerberine AlkaloidsBromodeoxyuridineChloroformCisplatincoptisineDrugs, Chinese HerbalHydrochloric AcidIsoquinolinesMethanolSolventsWaterberberineCoptis chinensis FranchcoptisineCPC chromatography techniquegastric cancerisoquinoline alkaloidsjatrorrhizinepalmatinezebrafish

Identifiers

PMID36142236
PMCPMC9499618

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.