Evidence map›Paper›PMID 36142173›Full record

ArticleInternational journal of molecular sciences2022

Implication of miR-155-5p and miR-143-3p in the Vascular Insulin Resistance and Instability of Human and Experimental Atherosclerotic Plaque.

Paula González-López, Carla Ares-Carral, Andrea R López-Pastor, Jorge Infante-Menéndez, Tamara González Illaness, Melina Vega de Ceniga, Leticia Esparza, Nuria Beneit, José Luis Martín-Ventura, Óscar Escribano and 1 more

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
2.2field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 26 citations in OpenAlex.

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  8. Mechanistic insight into the role of cardiac-enriched microRNAs in diabetic heart injury.American journal of physiology. Heart and circulatory physiology · 2025
    Review
  9. Article
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  11. Exosomal miR-155-5p promote the occurrence of carotid atherosclerosis.Journal of cellular and molecular medicine · 2024
    Article
  12. Article
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  18. Article
  19. MicroRNA, Insulin Resistance, and Metabolic Disorders.International journal of molecular sciences · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Paula González-LópezHepatic and Vascular Diseases Laboratory, Biochemistry and Molecular Biology Department, School of Pharmacy, Complutense University of Madrid, 28040 Madrid, Spain.ORCID 0000-0001-5848-0172
Carla Ares-CarralHepatic and Vascular Diseases Laboratory, Biochemistry and Molecular Biology Department, School of Pharmacy, Complutense University of Madrid, 28040 Madrid, Spain.
Andrea R López-PastorHepatic and Vascular Diseases Laboratory, Biochemistry and Molecular Biology Department, School of Pharmacy, Complutense University of Madrid, 28040 Madrid, Spain.ORCID 0000-0002-0054-3828
Jorge Infante-MenéndezHepatic and Vascular Diseases Laboratory, Biochemistry and Molecular Biology Department, School of Pharmacy, Complutense University of Madrid, 28040 Madrid, Spain.ORCID 0000-0003-0303-6538
Tamara González IllanessHepatic and Vascular Diseases Laboratory, Biochemistry and Molecular Biology Department, School of Pharmacy, Complutense University of Madrid, 28040 Madrid, Spain.ORCID 0000-0001-7351-5599
Melina Vega de CenigaDepartment of Angiology and Vascular Surgery, Hospital de Galdakao-Usansolo, 48960 Galdakao, Spain.
Leticia EsparzaDepartment of Angiology and Vascular Surgery, Hospital de Galdakao-Usansolo, 48960 Galdakao, Spain.
Nuria BeneitHepatic and Vascular Diseases Laboratory, Biochemistry and Molecular Biology Department, School of Pharmacy, Complutense University of Madrid, 28040 Madrid, Spain.
José Luis Martín-VenturaIIS-Fundation Jimenez-Diaz, Autonoma University of Madrid, 28040 Madrid, Spain.
Óscar EscribanoHepatic and Vascular Diseases Laboratory, Biochemistry and Molecular Biology Department, School of Pharmacy, Complutense University of Madrid, 28040 Madrid, Spain.ORCID 0000-0002-8249-1645
Almudena Gómez-HernándezHepatic and Vascular Diseases Laboratory, Biochemistry and Molecular Biology Department, School of Pharmacy, Complutense University of Madrid, 28040 Madrid, Spain.
Universidad Complutense de Madrid · ESBioCruces Health research Institute · ESCentro de Investigación en Red en Enfermedades Cardiovasculares · ES

Funding

Ministerio de Ciencia e Innovación y Universidades RTI-2018-095098-B100Santander-UCM PR75/18-21572
6 · The paper itself

Abstract

(1) Background: Cardiovascular diseases (CVDs) are the main cause of death in developed countries, being atherosclerosis, a recurring process underlying their apparition. MicroRNAs (miRNAs) modulate the expression of their targets and have emerged as key players in CVDs; (2) Methods: 18 miRNAs were selected (Pubmed and GEO database) for their possible role in promoting atherosclerosis and were analysed by RT-qPCR in the aorta from apolipoprotein E-deficient (

Indexed as

AtherosclerosisInsulin ResistanceMicroRNAsPlaque, AtheroscleroticAnimalsApolipoproteins EHumansInsulinMiceProto-Oncogene Proteins c-aktSomatomedinsApolipoproteins EInsulinMicroRNAsMIRN143 microRNA, humanMIRN155 microRNA, humanMirn155 microRNA, mouseProto-Oncogene Proteins c-aktSomatomedinsAKTapoptosisatherosclerosisIGF-IIRmiR-143-3pmiR-155-5punstable plaque

Identifiers

PMID36142173
PMCPMC9499612
OpenAlexW4296803456

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.