Evidence map›Paper›PMID 36141674›Full record

SynthesisInternational journal of environmental research and public health2022

Exploring Oral Microbiome in Healthy Infants and Children: A Systematic Review.

Silvia D'Agostino, Elisabetta Ferrara, Giulia Valentini, Sorana Andreea Stoica, Marco Dolci

Open access · goldAbstract readSystematic Review
In one paragraph

Synthesis in International journal of environmental research and public health, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed, 1 pooled it
5.0field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 1 synthesis or guideline pooled it, 35 citations in OpenAlex.

  1. Pooled it
  2. Human Oral-AssociatedMicroorganisms · 2026
    Review
  3. Article
  4. Review
  5. Multicohort external validation ofFrontiers in cellular and infection microbiology · 2026
    Article
  6. Article
  7. Article
  8. Article
  9. Review
  10. Article
  11. Review
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Review
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Silvia D'AgostinoDepartment of Interdisciplinary Medicine, University A. Moro, 70124 Bari, Italy.ORCID 0000-0002-4778-4768
Elisabetta FerraraDepartment of Medical, Oral and Biotechnological Sciences, University G. d'Annunzio, 66100 Chieti, Italy.ORCID 0000-0002-4831-4098
Giulia ValentiniDepartment of Medical, Oral and Biotechnological Sciences, University G. d'Annunzio, 66100 Chieti, Italy.
Sorana Andreea StoicaDepartment of Medical, Oral and Biotechnological Sciences, University G. d'Annunzio, 66100 Chieti, Italy.
Marco DolciDepartment of Medical, Oral and Biotechnological Sciences, University G. d'Annunzio, 66100 Chieti, Italy.ORCID 0000-0001-5495-5660
University of Chieti-Pescara · ITUniversity of Bari Aldo Moro · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Recent advances in the development of next-generation sequencing (NGS) technologies, such as the 16S rRNA gene sequencing, have enabled significant progress in characterizing the architecture of the oral microbiome. Understanding the taxonomic and functional components of the oral microbiome, especially during early childhood development, is becoming critical for identifying the interactions and adaptations of bacterial communities to dynamic conditions that may lead to the dysfunction of the host environment, thereby contributing to the onset and/or progression of a wide range of pathological conditions. We aimed to provide a comprehensive overview of the most recent evidence from studies of the oral microbiome of infants and young children, focusing on the development of oral microbiome in the window of birth to 18 years, focusing on infants. A systematic literature search was conducted in

Indexed as

MicrobiotaAdolescentBacteriaChildChild, PreschoolHigh-Throughput Nucleotide SequencingHumansInfantInfant, NewbornRNA, Ribosomal, 16SRNA, Ribosomal, 16S16S rRNA sequencingadolescentchildrenhealthy microbiomeinfantsoral microbiomepediatric dentistry

Identifiers

PMID36141674
PMCPMC9517473
OpenAlexW4296804070

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.