Evidence map›Paper›PMID 36141235›Full record

ArticleHealthcare (Basel, Switzerland)2022

Tackling Thyroid Cancer in Europe-The Challenges and Opportunities.

Denis Horgan, Dagmar Führer-Sakel, Paula Soares, Clara V Alvarez, Laura Fugazzola, Romana T Netea-Maier, Barbara Jarzab, Marta Kozaric, Beate Bartes, James Schuster-Bruce and 3 more

Open access · goldAbstract read
In one paragraph

Article in Healthcare (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
2.2field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 18 citations in OpenAlex.

  1. Genomics and Multi-Omics to Guide Clinical Management in Thyroid Cancer.International journal of molecular sciences · 2026
    Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Review
  8. Article
  9. Article
  10. Article
  11. Article
  12. Review
  13. Review
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 10 institutions in 9 countries.

Denis HorganEuropean Alliance for Personalised Medicine, 1040 Brussels, Belgium.
Dagmar Führer-SakelDepartment of Endocrinology, Diabetes and Metabolism, Endocrine Tumour Center at West German Cancer Center, University Hospital Essen, University of Duisburg-Essen, 45122 Duisburg, Germany.
Paula SoaresInstituto de Inovação e Investigação em Saúde/Institute of Molecular Pathology and Immunology of University of Porto (I3S/IPATIMUP), 4200-465 Porto, Portugal.ORCID 0000-0001-9607-6998
Clara V AlvarezNeoplasia & Endocrine Differentiation, Centro de Investigación en Medicina Molecular y Enfermedades Crónicas (CIMUS), University of Santiago de Compostela (USC), 15782 Santiago de Compostela, Spain.ORCID 0000-0003-1500-4058
Laura FugazzolaDivision of Endocrine and Metabolic Diseases, IRCCS Istituto Auxologico Italiano, 20145 Milan, Italy.ORCID 0000-0001-5372-0982
Romana T Netea-MaierDivision of Endocrinology, Department of Internal Medicine, Radboud University Medical Center, 6525 GA Nijmegen, The Netherlands.ORCID 0000-0002-9603-0460
Barbara JarzabDepartment of Nuclear Medicine and Endocrine Oncology, Maria Sklodowska-Curie National Research Institute of Oncology Gliwice Branch, 44-102 Gliwice, Poland.ORCID 0000-0001-9811-9584
Marta KozaricEuropean Alliance for Personalised Medicine, 1040 Brussels, Belgium.
Beate BartesAssociation Vivre sans Thyroïde, 31490 Léguevin, France.
James Schuster-BruceDepartment of Otolaryngology, Saint George's University Hospitals NHS Foundation Trust, London SW17 0QT, UK.
Luigino Dal MasoCancer Epidemiology Unit, Centro di Riferimento Oncologico di Aviano (CRO), 33081 Aviano, Italy.ORCID 0000-0001-6163-200X
Martin SchlumbergerDepartment of Nuclear Medicine and Endocrine Oncology, Institut Gustave Roussy, Université Paris Saclay, 94805 Villejuif, France.
Furio PaciniSection of Endocrinology, University of Siena, 53100 Siena, Italy.
Centro di Riferimento Oncologico · ITRadboud University Nijmegen · NLSt George’s University Hospitals NHS Foundation Trust · GBThe Maria Sklodowska-Curie National Research Institute of Oncology · PLUniversidade de Santiago de Compostela · ESUniversidade do Porto · PTUniversité Paris-Saclay · FRUniversity of Duisburg-Essen · DEUniversity of Milan · ITUniversity of Siena · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Thyroid cancer (TC) is the most common malignancy of the endocrine system that affects the thyroid gland. It is usually treatable and, in most cases, curable. The central issues are how to improve knowledge on TC, to accurately identify cases at an early stage that can benefit from effective intervention, optimise therapy, and reduce the risk of overdiagnosis and unnecessary treatment. Questions remain about management, about treating all patients in referral centres, and about which treatment should be proposed to any individual patient and how this can be optimised. The European Alliance for Personalised Medicine (EAPM) hosted an expert panel discussion to elucidate some of the challenges, and to identify possible steps towards effective responses at the EU and member state level, particularly in the context of the opportunities in the European Union's evolving initiatives-notably its Beating Cancer Plan, its Cancer Mission, and its research funding programmes. Recommendations emerging from the panel focus on improved infrastructure and funding, and on promoting multi-stakeholder collaboration between national and European initiatives to complement, support, and mutually reinforce efforts to improve patient care.

Indexed as

challengesdiagnosisopportunitiespersonalised medicinepolicy frameworkrare cancerthyroid cancertreatment

Identifiers

PMID36141235
PMCPMC9498891
OpenAlexW4293103610

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.