Evidence map›Paper›PMID 36140996›Full record

ArticleFoods (Basel, Switzerland)2022

Amino Acid Fingerprinting of Authentic Nonfat Dry Milk and Skim Milk Powder and Effects of Spiking with Selected Potential Adulterants.

Sneh D Bhandari, Tiffany Gallegos-Peretz, Thomas Wheat, Gregory Jaudzems, Natalia Kouznetsova, Katya Petrova, Dimple Shah, Daniel Hengst, Erika Vacha, Weiying Lu and 3 more

Open access · goldAbstract read
In one paragraph

Article in Foods (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.5field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 5 institutions in 3 countries.

Sneh D BhandariMerieux NutriSciences, 3600 Eagle Nest Drive, Crete, IL 60417, USA.
Tiffany Gallegos-PeretzFutureCeuticals, 2692 N. State Rt. 1-17, Momence, IL 60954, USA.
Thomas WheatWaters Corporation, 34 Maple Street, Milford, MA 01757, USA.
Gregory JaudzemsNestlé Quality Assurance Center, 6625 Eiterman Rd., Dublin, OH 43017, USA.
Natalia KouznetsovaUnited States Pharmacopeia (USP), 12601 Twinbrook Parkway, Rockville, MD 20852, USA.
Katya PetrovaUnited States Pharmacopeia (USP), 12601 Twinbrook Parkway, Rockville, MD 20852, USA.
Dimple ShahWaters Corporation, 34 Maple Street, Milford, MA 01757, USA.
Daniel HengstEurofins Food Integrity and Innovation, Madison, WI 53704, USA.
Erika VachaEurofins Food Integrity and Innovation, Madison, WI 53704, USA.
Weiying LuInstitute of Food and Nutraceutical Science, Department of Food Science and Technology, School of Agriculture and Biology, Shanghai Jiao Tong University, Shanghai 200240, China.
Jeffrey C MooreUnited States Pharmacopeia (USP), 12601 Twinbrook Parkway, Rockville, MD 20852, USA.
Pierre MetraMerieux NutriSciences Corporation, 113 Route de Paris, 69160 Tassin la Demi-Lune, France.
Zhuohong XieUnited States Pharmacopeia (USP), 12601 Twinbrook Parkway, Rockville, MD 20852, USA.ORCID 0000-0001-8009-3523
United States Pharmacopeial Convention · USEurofins (United States) · USWaters (United States) · USInstitut Mérieux (France) · FRShanghai Jiao Tong University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A collaborative study was undertaken in which five international laboratories participated to determine amino acid fingerprints in 39 authentic nonfat dry milk (NFDM)/skim milk powder (SMP) samples. A rapid method of amino acid analysis involving microwave-assisted hydrolysis followed by ultra-high performance liquid chromatography-ultraviolet detection (UHPLC-UV) was used for quantitation of amino acids and to calculate their distribution. The performance of this rapid method of analysis was evaluated and was used to determine the amino acid fingerprint of authentic milk powders. The distribution of different amino acids and their predictable upper and lower tolerance limits in authentic NFDM/SMP samples were established as a reference. Amino acid fingerprints of NFDM/SMP were compared with selected proteins and nitrogen rich compounds (proteins from pea, soy, rice, wheat, whey, and fish gelatin) which can be potential economically motivated adulterants (EMA). The amino acid fingerprints of NFDM/SMP were found to be affected by spiking with pea, soy, rice, whey, fish gelatin and arginine among the investigated adulterants but not by wheat protein and melamine. The study results establish an amino acid fingerprint of authentic NFDM/SMP and demonstrate the utility of this method as a tool in verifying the authenticity of milk powders and detecting their adulteration.

Indexed as

adulterationamino acidsauthenticationchromatographymicrowave-assisted hydrolysismilk powder

Identifiers

PMID36140996
PMCPMC9498471
OpenAlexW4296307151

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.