ReviewFoods (Basel, Switzerland)2022
The Formation, Structural Characteristics, Absorption Pathways and Bioavailability of Calcium-Peptide Chelates.
Review in Foods (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
16 citing papers in PubMed, 48 citations in OpenAlex.
- Effects of phytase and protease supplementation, with and without considering their nutritional matrix values, on the productive performance of laying hens during the late‑lay period.Veterinary and animal science · 2026Article
- Bioactive Peptide-Enriched Requeson: A Functional Dairy Product From Whey Fermentation.Food science & nutrition · 2026Article
- Intestinal Microbiota Mediates the Beneficial Effects of γ-Polyglutamic Acid on Calcium Homeostasis and Bone Properties in Lambs.International journal of molecular sciences · 2026Article
- Food-derived protein-based calcium chelates: digestive stability, intestinal transport, and bone-related functions.Frontiers in nutrition · 2026Review
- A dual absorption pathway of novel oyster-derived peptide-zinc complex enhances zinc bioavailability and restores mitochondrial function.Journal of advanced research · 2025Article
- Progress in peptide and protein therapeutics: Challenges and strategies.Acta pharmaceutica Sinica. B · 2025Review
- Preparation, Structural Characterization, and Calcium Supplementation Activity ofFoods (Basel, Switzerland) · 2025Article
- Study on the Calcium Transport-Promoting Property and Mechanism of the Peptide-Calcium Complex DEEENDQVK-Ca Based on a Caco-2 Monolayer Model.Foods (Basel, Switzerland) · 2025Article
- Novel Insights Into Peptide-Calcium Chelates FromFood science & nutrition · 2025Article
- Investigating the Role of Food-Derived Peptides in Hyperuricemia: From Mechanisms of Action to Structural Effects.Foods (Basel, Switzerland) · 2024Review
- Non-Covalent Interaction of Folic Acid and 5-Methyltetrahydrofolate with Caseinates Improves the Folates Stability Studied by Multi-Spectroscopic Analysis and Molecular Docking.Foods (Basel, Switzerland) · 2024Article
- Article
- Study on the Changes of Bone Calcium during the Fermentation of Bone Powders with Different Fermenters.Foods (Basel, Switzerland) · 2024Article
- Dexamethasone-Loaded Lipid Calcium Phosphate Nanoparticles Treat Experimental Colitis by Regulating Macrophage Polarization in Inflammatory Sites.International journal of nanomedicine · 2024Article
- Recent Trends in Cereal- and Legume-Based Protein-Mineral Complexes: Formulation Methods, Toxicity, and Food Applications.Foods (Basel, Switzerland) · 2023Review
- Preparation, Structural Characterization, and Stability of Low-Molecular-Weight Collagen Peptides-Calcium Chelate Derived from Tuna Bones.Foods (Basel, Switzerland) · 2023Article
Corrections and comments
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Authors and funding
7 authors at 1 institution in 1 country.
Funding
Abstract
Calcium is one of the most important mineral elements in the human body and is closely related to the maintenance of human health. To prevent calcium deficiency, various calcium supplements have been developed, but their application tends to be limited by low calcium content and highly irritating effects on the stomach, among other side effects. Recently, calcium-peptide chelates, which have excellent stability and are easily absorbed, have received attention as an alternative emerging calcium supplement. Calcium-binding peptides (CaBP) are usually obtained via the hydrolysis of animal or plant proteins, and calcium-binding capacity (CaBC) can be further improved through chromatographic purification techniques. In calcium ions, the phosphate group, carboxylic group and nitrogen atom in the peptide are the main binding sites, and the four modes of combination are the unidentate mode, bidentate mode, bridging mode and α mode. The stability and safety of calcium-peptide chelates are discussed in this paper, the intestinal absorption pathways of calcium elements and peptides are described, and the bioavailability of calcium-peptide chelates, both in vitro and in vivo, is also introduced. This review of the research status of calcium-peptide chelates aims to provide a reasonable theoretical basis for their application as calcium supplementation products.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.