Evidence map›Paper›PMID 36140765›Full record

ReviewGenes2022

Forensic Applications of Markers Present on the X Chromosome.

Fernanda M Garcia, Bárbara G O Bessa, Eldamária V W Dos Santos, Julia D P Pereira, Lyvia N R Alves, Lucas A Vianna, Matheus C Casotti, Raquel S R Trabach, Victor S Stange, Débora D Meira and 1 more

Abstract readReview
In one paragraph

Review in Genes, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Fernanda M GarciaNúcleo de Genética Humana e Molecular-Departamento de Ciências Biológicas-Universidade Federal do Espírito Santo, Vitória 29075-910, Espirito Santo, Brazil.ORCID 0000-0002-7035-5005
Bárbara G O BessaNúcleo de Genética Humana e Molecular-Departamento de Ciências Biológicas-Universidade Federal do Espírito Santo, Vitória 29075-910, Espirito Santo, Brazil.
Eldamária V W Dos SantosNúcleo de Genética Humana e Molecular-Departamento de Ciências Biológicas-Universidade Federal do Espírito Santo, Vitória 29075-910, Espirito Santo, Brazil.
Julia D P PereiraNúcleo de Genética Humana e Molecular-Departamento de Ciências Biológicas-Universidade Federal do Espírito Santo, Vitória 29075-910, Espirito Santo, Brazil.ORCID 0000-0001-5443-1082
Lyvia N R AlvesNúcleo de Genética Humana e Molecular-Departamento de Ciências Biológicas-Universidade Federal do Espírito Santo, Vitória 29075-910, Espirito Santo, Brazil.
Lucas A ViannaLaboratório de DNA Forense-Polícia Civil do Espírito Santo, Vitória 29045-402, Espirito Santo, Brazil.
Matheus C CasottiNúcleo de Genética Humana e Molecular-Departamento de Ciências Biológicas-Universidade Federal do Espírito Santo, Vitória 29075-910, Espirito Santo, Brazil.
Raquel S R TrabachNúcleo de Genética Humana e Molecular-Departamento de Ciências Biológicas-Universidade Federal do Espírito Santo, Vitória 29075-910, Espirito Santo, Brazil.
Victor S StangeLaboratório de DNA Forense-Polícia Civil do Espírito Santo, Vitória 29045-402, Espirito Santo, Brazil.
Débora D MeiraNúcleo de Genética Humana e Molecular-Departamento de Ciências Biológicas-Universidade Federal do Espírito Santo, Vitória 29075-910, Espirito Santo, Brazil.
Iuri D LouroNúcleo de Genética Humana e Molecular-Departamento de Ciências Biológicas-Universidade Federal do Espírito Santo, Vitória 29075-910, Espirito Santo, Brazil.ORCID 0000-0001-5160-9615

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Microsatellite genetic markers are the gold standard for human genetic identification. Forensic analyses around the world are carried out through protocols using the analysis of STR markers in autosomal chromosomes and in the Y chromosome to solve crimes. However, these analyses do not allow for the resolution of all cases, such as rape situations with suspicion of incest, paternity without a maternal sample for comparison, and biological traces with DNA mixture where the profile sought is female, among other situations. In these complex cases, the study of X-chromosome STR markers significantly increases the probability of identification by complementing the data obtained for autosomal and Y-chromosome markers, due to the unique structure of the X chromosome and its exclusive method of inheritance. However, there are currently no validated Brazilian protocols for this purpose, nor are there any population data necessary for statistical analyses that must be included in the issuance of expert reports. Thus, the aim of this article is to provide a literary review of the applications of X-chromosomal markers in population genetics.

Indexed as

Chromosomes, Human, XForensic GeneticsDNAFemaleGenetic MarkersHumansMicrosatellite RepeatsDNAGenetic Markersforensic geneticskinship testingpopulation geneticsX chromosome markersX chromosome short tandem repeats (X-STRs)

Identifiers

PMID36140765
PMCPMC9498577

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.