Evidence map›Paper›PMID 36140578›Full record

ReviewDiagnostics (Basel, Switzerland)2022

Relationship between Coronary Arterial Geometry and the Presence and Extend of Atherosclerotic Plaque Burden: A Review Discussing Methodology and Findings in the Era of Cardiac Computed Tomography Angiography.

Georgios Rampidis, Vasileios Rafailidis, Konstantinos Kouskouras, Andjoli Davidhi, Angeliki Papachristodoulou, Athanasios Samaras, George Giannakoulas, Antonios Ziakas, Panagiotis Prassopoulos, Haralambos Karvounis

Registry-linked trialAbstract readReview
In one paragraph

Review in Diagnostics (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06029387 (Artificial Intelligence for Preventing Heart Disease), which is not on this map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06029387 completednot on this mapstarted 2023, after this paper: background citation

Artificial Intelligence for Preventing Heart Disease: Observational, Single Center, Prospective and Retrospective Study

TypeobservationalSponsorIRCCS San RaffaeleRan2023 to 2024Enrolled3,000ConditionsCoronary Artery Disease
3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Incidence and pattern of urgent revascularization in acute coronary syndromes treated with ticagrelor or prasugrel.Clinical research in cardiology : official journal of the German Cardiac Society · 2024
    Trial
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Georgios RampidisFirst Department of Cardiology, AHEPA University Hospital, Aristotle University of Thessaloniki, 54636 Thessaloniki, Greece.ORCID 0000-0002-2452-6942
Vasileios RafailidisDepartment of Radiology, AHEPA University Hospital, Aristotle University of Thessaloniki, 54636 Thessaloniki, Greece.
Konstantinos KouskourasDepartment of Radiology, AHEPA University Hospital, Aristotle University of Thessaloniki, 54636 Thessaloniki, Greece.
Andjoli DavidhiDepartment of Radiology, AHEPA University Hospital, Aristotle University of Thessaloniki, 54636 Thessaloniki, Greece.
Angeliki PapachristodoulouDepartment of Radiology, AHEPA University Hospital, Aristotle University of Thessaloniki, 54636 Thessaloniki, Greece.
Athanasios SamarasFirst Department of Cardiology, AHEPA University Hospital, Aristotle University of Thessaloniki, 54636 Thessaloniki, Greece.
George GiannakoulasFirst Department of Cardiology, AHEPA University Hospital, Aristotle University of Thessaloniki, 54636 Thessaloniki, Greece.ORCID 0000-0001-7491-6319
Antonios ZiakasFirst Department of Cardiology, AHEPA University Hospital, Aristotle University of Thessaloniki, 54636 Thessaloniki, Greece.
Panagiotis PrassopoulosDepartment of Radiology, AHEPA University Hospital, Aristotle University of Thessaloniki, 54636 Thessaloniki, Greece.
Haralambos KarvounisFirst Department of Cardiology, AHEPA University Hospital, Aristotle University of Thessaloniki, 54636 Thessaloniki, Greece.

Funding

European Social Fund-ESF MIS 5047882Menarini Hellas S.A 27.11.2020/72059
6 · The paper itself

Abstract

Coronary artery disease (CAD) represents a modern pandemic associated with significant morbidity and mortality. The multi-faceted pathogenesis of this entity has long been investigated, highlighting the contribution of systemic factors such as hyperlipidemia and hypertension. Nevertheless, recent research has drawn attention to the importance of geometrical features of coronary vasculature on the complexity and vulnerability of coronary atherosclerosis. Various parameters have been investigated so far, including vessel-length, coronary artery volume index, cross-sectional area, curvature, and tortuosity, using primarily invasive coronary angiography (ICA) and recently non-invasive cardiac computed tomography angiography (CCTA). It is clear that there is correlation between geometrical parameters and both the haemodynamic alterations augmenting the atherosclerosis-prone environment and the extent of plaque burden. The purpose of this review is to discuss the currently available literature regarding this issue and propose a potential non-invasive imaging biomarker, the geometric risk score, which could be of importance to allow the early detection of individuals at increased risk of developing CAD.

Indexed as

atherosclerosiscardiac CTcoronarygeometry

Identifiers

PMID36140578
PMCPMC9497479

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.