Evidence map›Paper›PMID 36140570›Full record

ArticleDiagnostics (Basel, Switzerland)2022

The Influence of Eyelid Position and Environmental Conditions on the Corneal Changes in Early Postmortem Interval: A Prospective, Multicentric OCT Study.

Matteo Nioi, Pietro Emanuele Napoli, Roberto Demontis, Alberto Chighine, Fabio De-Giorgio, Simone Grassi, Vincenzo Scorcia, Maurizio Fossarello, Ernesto d'Aloja

Open access · goldAbstract read
In one paragraph

Article in Diagnostics (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
1.2field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 6 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Matteo NioiForensic Medicine Unit, Department of Clinical Sciences and Public Health, University of Cagliari, 09124 Cagliari, Italy.ORCID 0000-0002-3645-6005
Pietro Emanuele NapoliEye Clinic, Department of Surgical Science, University of Cagliari, 09124 Cagliari, Italy.ORCID 0000-0001-7020-0823
Roberto DemontisForensic Medicine Unit, Department of Clinical Sciences and Public Health, University of Cagliari, 09124 Cagliari, Italy.ORCID 0000-0003-2306-9767
Alberto ChighineForensic Medicine Unit, Department of Clinical Sciences and Public Health, University of Cagliari, 09124 Cagliari, Italy.ORCID 0000-0003-0952-9712
Fabio De-GiorgioLegal Medicine, Department of Health Surveillance and Bioethics, Università Cattolica del Sacro Cuore, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, 00168 Rome, Italy.ORCID 0000-0001-7433-0924
Simone GrassiLegal Medicine, Department of Health Surveillance and Bioethics, Università Cattolica del Sacro Cuore, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, 00168 Rome, Italy.
Vincenzo ScorciaDepartment of Ophthalmology, University 'Magna Græcia' of Catanzaro, Viale Europa, 88100 Catanzaro, Italy.ORCID 0000-0001-6826-7957
Maurizio FossarelloEye Clinic, Department of Surgical Science, University of Cagliari, 09124 Cagliari, Italy.ORCID 0000-0003-1520-7760
Ernesto d'AlojaForensic Medicine Unit, Department of Clinical Sciences and Public Health, University of Cagliari, 09124 Cagliari, Italy.
University of Cagliari · ITUniversità Cattolica del Sacro Cuore · ITMagna Graecia University · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In the current study, using portable optical coherence tomography, we evaluated 46 corneas of 23 individuals in a multicenter setting during the first 17 h after death. Twenty-three eyes were kept open, and twenty three were kept closed. Furthermore, the experiment was carried out for 12 samples in summer and 11 in winter. Our data show that postmortem corneal alterations largely depend on the phenomena of dehydration (in particular in open eyes) and swelling of the stroma in closed eyes, probably due in the first phase to hypoxia/anoxia and subsequently to the passage by osmosis of the aqueous humor from the anterior chamber to the corneal tissue. Our findings could have significant repercussions in forensic pathology for estimating the postmortem interval and transplantation to optimize the conservation of the tissue before the explant.

Indexed as

corneacorneal transplantforensic imagingforensic pathologypostmortem eyepostmortem intervalpostmortem ocular changespostmortem optical coherence tomography

Identifiers

PMID36140570
PMCPMC9497849
OpenAlexW4295106559

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.