ReviewBiomedicines2022
Biodegradation of Dental Resin-Based Composite-A Potential Factor Affecting the Bonding Effect: A Narrative Review.
Review in Biomedicines, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
25 citing papers in PubMed, 1 synthesis or guideline pooled it, 53 citations in OpenAlex.
- Considerations about Cytotoxicity of Resin-Based Composite Dental Materials: A Systematic Review.International journal of molecular sciences · 2023Pooled it
- Cytotoxic Effects of Flowable Composite Resins with Different Resin Matrix Compositions on L929 Fibroblasts.Oral health & preventive dentistry · 2026Article
- Three-Dimensional Assessment of Composite Attachment Wear in Clear Aligner Therapy: A Prospective Cohort Study.Cureus · 2026Article
- Effect of Simulated Oral Aging on Surface Roughness and Microhardness of Bulk-Fill Composite Resins.Dentistry journal · 2026Article
- RETRACTED: Surface gloss and micro-CT analysis of additively and subtractively manufactured resin composites and zirconia after simulated tooth brushing with different bristle types and toothpaste formulations: An in vitro study.Journal of prosthodontics : official journal of the American College of Prosthodontists · 2026Article
- Bisphenol-A Release from Modern Resin-Based Dental Composites: A Time-Dependent In Vitro Assessment.Polymers · 2026Article
- Cyclic Acidic Beverage Exposure Induces Formulation-Dependent Mechanical Softening and Tribological Alterations in Microhybrid and Nanohybrid Dental Resin Composites.Journal of functional biomaterials · 2026Article
- Comparative Evaluation of Commercial Bulk-Fill Resin-Based Composites: Flexural Properties, Roughness, Water Sorption and Solubility, and Color Stability.Dentistry journal · 2026Article
- Comparative analysis of polymerization efficiency and degradation indicators of adhesive resin cements and preheated restorative composites.Scientific reports · 2026Article
- Comparative Evaluation of Mechanical Properties, Color Stability, and Surface Roughness of Gingiva-Shaded Composites.International journal of dentistry · 2026Article
- Bisphenol A in contemporary dentistry: from material chemistry and exposure pathways to potential clinical relevance-a comprehensive narrative review.Frontiers in dental medicine · 2026Review
- Current Developments in Antibacterial Nanoparticle-Based Dental Composite Materials: A Comprehensive Overview.International journal of dentistry · 2026Review
- Multifunctional resin-matrix ceramic: synergistic mechanical-biological optimization and novel strategies for translational research.RSC advances · 2025Review
- The Influence of Thermocycling and Ultraviolet Aging on Surface Characteristics and the Repair Bond Strength of CAD/CAM Resin Nanoceramics.Journal of functional biomaterials · 2025Article
- The Biodegradation of Acrylic-Coated Woven Fabrics byMaterials (Basel, Switzerland) · 2025Article
- [Effects of cell area on single odontoblast polarization and differentiation via microarray technology].Hua xi kou qiang yi xue za zhi = Huaxi kouqiang yixue zazhi = West China journal of stomatology · 2025Article
- The Effect of Chemical Surface Modification on the Repair Bond Strength of Resin Composite: An In Vitro Study.Polymers · 2025Article
- Towards the Standardization of Artificial Aging Protocols for Dental Composites: Evaluation of Proposed Methods.Journal of functional biomaterials · 2025Article
- Synergistic effects of bacteria, enzymes, and cyclic mechanical stresses on the bond strength of composite restorations.Biomaterials advances · 2025Article
- Effect of finishing and polishing systems on surface roughness and color stability of aesthetic restorations exposed to staining solution.Acta odontologica latinoamericana : AOL · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In recent years, although resin composite has played an important role in the restoration of tooth defects, it still has several disadvantages, including being biodegraded by saliva, bacteria and other enzymes in the oral cavity, which may result in repair failure. This factor is not conducive to the long-term survival of the prosthesis in the mouth. In this article, we review the causes, influencing factors and prevention methods of resin biodegradation. Biodegradation is mainly caused by esterase in saliva and bacteria, which breaks the ester bond in resin and causes the release of monomers. The mechanical properties of the prosthesis can then be affected. Meanwhile, cathepsin and MMPs are activated on the bonding surface, which may decompose the dentin collagen. In addition, neutrophils and residual water on the bonding surface can also aggravate biodegradation. Currently, the primary methods to prevent biodegradation involve adding antibacterial agents to resin, inhibiting the activity of MMPs and enhancing the crosslinking of collagen fibers. All of the above indicates that in the preparation and adhesion of resin materials, attention should be paid to the influence of biodegradation to improve the prosthesis's service life in the complex environment of the oral cavity.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.