Evidence map›Paper›PMID 36140325›Full record

ReviewBiomedicines2022

Nephron-Sparing Approaches in Upper Tract Urothelial Carcinoma: Current and Future Strategies.

Won Sik Ham, Jee Soo Park, Won Sik Jang, Jongchan Kim

Registry-linked trialOpen access · goldAbstract readReview
In one paragraph

Review in Biomedicines, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07077447 (DaBlaCa 23 - The European Collaborative Study on Upper Urinary Tract Urothelial Carcinoma), which is not on this map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
1.7field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07077447 recruitingnot on this mapstarted 2025, after this paper: background citation

DaBlaCa 23 - The European Collaborative Study on Upper Urinary Tract Urothelial Carcinoma

TypeobservationalSponsorZealand University HospitalRan2025 to 2040Enrolled2,500ConditionsUpper Urinary Tract Urothelial CarcinomaArmsKidney sparing surgery for high-risk upper urinary tract urothelial carcinoma
3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 8 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Review
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Won Sik HamDepartment of Urology, Urological Science Institute, Yonsei University College of Medicine, Seoul 03722, Korea.ORCID 0000-0003-2246-8838
Jee Soo ParkDepartment of Urology, Urological Science Institute, Yonsei University College of Medicine, Seoul 03722, Korea.ORCID 0000-0001-9976-6599
Won Sik JangDepartment of Urology, Urological Science Institute, Yonsei University College of Medicine, Seoul 03722, Korea.ORCID 0000-0002-9082-0381
Jongchan KimDepartment of Urology, Urological Science Institute, Yonsei University College of Medicine, Seoul 03722, Korea.ORCID 0000-0002-0022-6689
Yonsei University · KR

Funding

Korea Health Industry Development Institute HI17C1095National Research Foundation of Korea 2019R1A2C1002863National Research Foundation of Korea 2022R1A2C2003831
6 · The paper itself

Abstract

Upper tract urothelial carcinoma (UTUC) is a relatively rare cancer, and much of the approach to treatment has been derived from strategies employed in treating bladder cancer. Radical nephroureterectomy (RNU) is regarded as the gold standard treatment for UTUC. However, due to potential complications, such as renal function impairment, that can affect oncologic outcomes, the demand for nephron-sparing treatment to effectively treat cancer while preserving renal function has increased. As a result, various treatment methods for low-grade, low-volume UTUC, such as segmental ureterectomy, endoscopic resection, and intraluminal therapy, have been attempted and reported. Although these treatment modalities have exhibited acceptable oncological results, further studies are required. In the future, the introduction of new technologies, such as improved diagnostic and surgical equipment, and new drug delivery systems, could enhance the effectiveness of nephron-sparing strategies in the treatment of UTUC. Additionally, understanding the biological and genetic characteristics of UTUC that distinguish it from those of bladder cancer will also aid in establishing strategies for nephron-sparing.

Indexed as

kidney functionnephron-sparingupper urinary tracturothelial carcinoma

Identifiers

PMID36140325
PMCPMC9496458
OpenAlexW4296111595

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.