ReviewBiomedicines2022
Electroencephalographic Patterns in taVNS: A Systematic Review.
Review in Biomedicines, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06193317 (Effects of taVNS on Fibromyalgia Pain), which is not on this map. Cited by 23 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Effects of taVNS on Fibromyalgia Pain
Who cites it
23 citing papers in PubMed, 1 synthesis or guideline pooled it, 36 citations in OpenAlex.
- Vagus Nerve Stimulation in the Management of Neurodegenerative Diseases: A Systematic Review of Advances in Animal Research and Clinical Applications.Current Alzheimer research · 2026Pooled it
- Efficacy and safety of transcutaneous auricular vagus nerve stimulation for patients with treatment-resistant schizophrenia with predominantly negative symptoms: a randomized clinical trial and efficacy sensitivity biomarkers.Molecular psychiatry · 2025Trial
- The effects of non-invasive transcutaneous auricular vagus nerve stimulation on resting-state delta oscillation: a randomized, double-blinded, sham-control trial.Scientific reports · 2025Trial
- Influence of a 2-week transcutaneous auricular vagus nerve stimulation on memory: findings from a randomized placebo controlled trial in non-clinical adults.Clinical autonomic research : official journal of the Clinical Autonomic Research Society · 2024Trial
- Efficacy and EEG-ECG mechanisms of taVNS combined with TEAS for negative symptoms of schizophrenia: a protocol for a 2 × 2 factorial randomized controlled trial.European archives of psychiatry and clinical neuroscience · 2026Article
- Effects of Transcutaneous Vagus Nerve Stimulation, Neurofeedback, and their Combination on Cortisol, Anxiety, and Depression Subtypes in Non-Clinical Adults.Applied psychophysiology and biofeedback · 2026Article
- Transcutaneous auricular vagus nerve stimulation, tolerability, and the Alpha/Theta EEG ratio: a controlled pilot study relevant to emotion regulation.Frontiers in psychiatry · 2026Article
- Transcutaneous auricular vagus nerve stimulation: mechanisms, applications, and research progress.Frontiers in neuroscience · 2026Review
- Mechanistic insights into combined prefrontal tDCS and vagal nerve stimulation for stress regulation.Frontiers in psychology · 2026Review
- Perioperative transcutaneous auricular vagus nerve stimulation and EEG biomarkers of sleep improvement after gynecologic laparoscopy: protocol for a randomized controlled trial.Frontiers in medicine · 2026Article
- Transcutaneous auricular vagus nerve stimulation for major depressive disorder: current evidence and future research directions.Frontiers in psychiatry · 2026Review
- Effects of transcutaneous auricular vagus nerve stimulation on associative memory, event-related potential P300 and P600: a single-blind pilot experiment on healthy adults.Experimental brain research · 2025Article
- Article
- Transcutaneous Vagus Nerve Stimulation Effects on Flavor-Evoked Electroencephalogram and Eye-Blink Rate.Brain and behavior · 2025Article
- Changes in brain functional connectivity associated with transcutaneous auricular vagus nerve stimulation in healthy controls.Frontiers in human neuroscience · 2025Article
- Task-specific cortical mechanisms of taVNS-paired task-oriented training for post-stroke upper extremity dysfunction under cognitive load: an fNIRS study.Frontiers in human neuroscience · 2025Article
- Vagus nerve electrical stimulation in the recovery of upper limb motor functional impairment after ischemic stroke.Cognitive neurodynamics · 2024Review
- Impact of Stimulation Duration in taVNS-Exploring Multiple Physiological and Cognitive Outcomes.Brain sciences · 2024Article
- Investigating neuromodulatory effect of transauricular vagus nerve stimulation on resting-state electroencephalography.Biomedical engineering letters · 2024Article
- Transcutaneous auricular vagus nerve stimulation on upper limb motor function with stroke: a functional near-infrared spectroscopy pilot study.Frontiers in neuroscience · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 4 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Transcutaneous auricular vagus nerve stimulation (taVNS) is a newer delivery system using a non-invasive stimulation device placed at the ear. taVNS research is focused on clinical trials showing potential therapeutic benefits, however the neurophysiological effects of this stimulation on brain activity are still unclear. We propose a systematic review that aims to describe the effects of taVNS on EEG measures and identify taVNS parameters that can potentially lead to consistent EEG-mediated biomarkers for this therapy. A systematic literature review was carried out following the Preferred Reporting Items for Systematic Reviews and Meta-Analyzes (PRISMA) and the Cochrane handbook for systematic reviews. Clinical trials examining EEG parameters were considered, including absolute and relative power, coherence, degree of symmetry, evoked potentials, and peak frequency of all bands. According to our criteria, 18 studies (from 122 articles) were included. Our findings show a general trend towards increased EEG power spectrum activity in lower frequencies, and changes on early components of the ERP related to inhibitory tasks. This review suggests that quantitative electroencephalography can be used to assess the effects of taVNS on brain activity, however more studies are needed to systematically establish the specific effects and metrics that would reflect the non-invasive stimulation through the auricular branch of the vagus nerve.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.