Evidence map›Paper›PMID 36140268›Full record

ReviewBiomedicines2022

Understanding Acquired Brain Injury: A Review.

Liam Goldman, Ehraz Mehmood Siddiqui, Andleeb Khan, Sadaf Jahan, Muneeb U Rehman, Sidharth Mehan, Rajat Sharma, Stepan Budkin, Shashi Nandar Kumar, Ankita Sahu and 2 more

Open access · goldAbstract readReview
In one paragraph

Review in Biomedicines, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 79 papers.

0numbers the graph read from it
0cells of the map it votes in
79citing papers in PubMed
13.2field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

79 citing papers in PubMed, 121 citations in OpenAlex.

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19 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 9 institutions in 3 countries.

Liam GoldmanDepartment of Neurosurgery, Medical College of Georgia, Augusta University, Augusta, GA 30912, USA.
Ehraz Mehmood SiddiquiDepartment of Pharmacology, Buddha Institute of Pharmacy, CL-1, Sector 7, Gorakhpur 273209, India.
Andleeb KhanDepartment of Pharmacology and Toxicology, College of Pharmacy, Jazan University, Jazan 45142, Saudi Arabia.ORCID 0000-0001-6125-3309
Sadaf JahanMedical Laboratories Department, College of Applied Medical Sciences, Majmaah University, Majmaah 15341, Saudi Arabia.ORCID 0000-0002-6976-5672
Muneeb U RehmanDepartment of Clinical Pharmacy, College of Pharmacy, King Saud University, Riyadh 11451, Saudi Arabia.ORCID 0000-0002-9995-6576
Sidharth MehanNeuropharmacology Division, Department of Pharmacology, ISF College of Pharmacy, Moga 142001, India.ORCID 0000-0003-0034-835X
Rajat SharmaDepartment of Neurosurgery, Medical College of Georgia, Augusta University, Augusta, GA 30912, USA.
Stepan BudkinDepartment of Neurosurgery, Medical College of Georgia, Augusta University, Augusta, GA 30912, USA.
Shashi Nandar KumarEnvironmental Toxicology Laboratory, ICMR-National Institute of Pathology, New Delhi 110029, India.
Ankita SahuTumor Biology Lab, ICMR-National Institute of Pathology, Safdarjung Hospital Campus, New Delhi 110029, India.ORCID 0000-0001-6679-3486
Manish KumarDepartment of Neurosurgery, Medical College of Georgia, Augusta University, Augusta, GA 30912, USA.
Kumar VaibhavDepartment of Neurosurgery, Medical College of Georgia, Augusta University, Augusta, GA 30912, USA.ORCID 0000-0002-4206-3830
Augusta University · USGautam Buddha University · INIndo Soviet Friendship College of Pharmacy · INJazan University · SAKing Saud University · SAMajmaah University · SANational Institute of Pathology · INSafdarjang Hospital · INThe Graduate Center, CUNY · US

Funding

Therapeutic Targeting of Monoacylglycerol Lipase After Traumatic Brain InjuryR01NS114560 · NINDS · AUGUSTA UNIVERSITY · PI VAIBHAV, KUMAR · 2020 to 2024
$1.8M
NINDS NIH HHS R01 NS114560
6 · The paper itself

Abstract

Any type of brain injury that transpires post-birth is referred to as Acquired Brain Injury (ABI). In general, ABI does not result from congenital disorders, degenerative diseases, or by brain trauma at birth. Although the human brain is protected from the external world by layers of tissues and bone, floating in nutrient-rich cerebrospinal fluid (CSF); it remains susceptible to harm and impairment. Brain damage resulting from ABI leads to changes in the normal neuronal tissue activity and/or structure in one or multiple areas of the brain, which can often affect normal brain functions. Impairment sustained from an ABI can last anywhere from days to a lifetime depending on the severity of the injury; however, many patients face trouble integrating themselves back into the community due to possible psychological and physiological outcomes. In this review, we discuss ABI pathologies, their types, and cellular mechanisms and summarize the therapeutic approaches for a better understanding of the subject and to create awareness among the public.

Indexed as

Acquired Brain Injury (ABI)brain functionsbrain impairmentcellular mechanismspathologiespost-birththerapeutic approach

Identifiers

PMID36140268
PMCPMC9496189
OpenAlexW4294989736

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.