Evidence map›Paper›PMID 36140222›Full record

ArticleBiomedicines2022

Neuroprotective Effects of the Lithium Salt of a Novel JNK Inhibitor in an Animal Model of Cerebral Ischemia-Reperfusion.

Igor A Schepetkin, Galina A Chernysheva, Oleg I Aliev, Liliya N Kirpotina, Vera I Smol'yakova, Anton N Osipenko, Mark B Plotnikov, Anastasia R Kovrizhina, Andrei I Khlebnikov, Evgenii V Plotnikov and 1 more

Open access · goldAbstract read
In one paragraph

Article in Biomedicines, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.0field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 12 citations in OpenAlex.

  1. Chemistry and Biological Activity of 11Molecules (Basel, Switzerland) · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 2 countries.

Igor A SchepetkinDepartment of Microbiology and Cell Biology, Montana State University, Bozeman, MT 59717, USA.
Galina A ChernyshevaDepartment of Pharmacology, Goldberg Research Institute of Pharmacology and Regenerative Medicine, Tomsk NRMC, 634028 Tomsk, Russia.
Oleg I AlievDepartment of Pharmacology, Goldberg Research Institute of Pharmacology and Regenerative Medicine, Tomsk NRMC, 634028 Tomsk, Russia.
Liliya N KirpotinaDepartment of Microbiology and Cell Biology, Montana State University, Bozeman, MT 59717, USA.
Vera I Smol'yakovaDepartment of Pharmacology, Goldberg Research Institute of Pharmacology and Regenerative Medicine, Tomsk NRMC, 634028 Tomsk, Russia.
Anton N OsipenkoDepartment of Pharmacology, Siberian State Medical University, 2 Moskovskiy tract, 634050 Tomsk, Russia.
Mark B PlotnikovDepartment of Pharmacology, Goldberg Research Institute of Pharmacology and Regenerative Medicine, Tomsk NRMC, 634028 Tomsk, Russia.ORCID 0000-0002-0548-6586
Anastasia R KovrizhinaKizhner Research Center, Tomsk Polytechnic University, 634050 Tomsk, Russia.
Andrei I KhlebnikovKizhner Research Center, Tomsk Polytechnic University, 634050 Tomsk, Russia.ORCID 0000-0002-3022-4510
Evgenii V PlotnikovResearch School of Chemistry and Applied Biomedical Sciences, Tomsk Polytechnic University, 634050 Tomsk, Russia.ORCID 0000-0002-4374-6422
Mark T QuinnDepartment of Microbiology and Cell Biology, Montana State University, Bozeman, MT 59717, USA.ORCID 0000-0001-8114-5073
National Research Tomsk State University · RUMontana State University · USResearch Institute of Pharmacology and Regenerative Medicine named ED Goldberg · RUSiberian State Medical University · RU

Funding

Research Core (Developmental Research Project Program)P20GM103474 · NIGMS · MONTANA STATE UNIVERSITY - BOZEMAN · PI Jeffrey Good · 2012 to 2026
$60.0M
Tracking and Evaluation CoreU54GM115371 · NIGMS · MONTANA STATE UNIVERSITY - BOZEMAN · PI QUINN, MARK T, RASMUS, STACY M. · 2016 to 2020
$20.9M
Ministry of Science and Higher Education of the Russian Federation FGWM-2022-0017NIGMS NIH HHS P20 GM103474NIGMS NIH HHS U54 GM115371NIH HHS GM103474NIH HHS GM115371Tomsk Polytechnic University Priority-2030-NIP/IZ-009-0000-2022United States Department of Agriculture 1009546
6 · The paper itself

Abstract

The c-Jun

Indexed as

11H-indeno[1,2-b]quinoxalin-11-onec-Jun N-terminal kinaseinterleukin-6lithium saltnuclear factor-κBoximestroke

Identifiers

PMID36140222
PMCPMC9495587
OpenAlexW4293527523

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.