Evidence map›Paper›PMID 36140163›Full record

ReviewBiomedicines2022

Immune Response to Biofilm Growing Pulmonary

Kim Thomsen, Niels Høiby, Peter Østrup Jensen, Oana Ciofu, Claus Moser

Open access · goldAbstract readReview
In one paragraph

Review in Biomedicines, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.1field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 13 citations in OpenAlex.

  1. Review
  2. Review
  3. Molecular Mechanisms Underlying the Pathogenicity ofMedicina (Kaunas, Lithuania) · 2026
    Review
  4. Review
  5. Review
  6. Review
  7. Diversification ofMicroorganisms · 2025
    Article
  8. Article
  9. Article
  10. Review
  11. Review
  12. Article
  13. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Kim ThomsenZealand University Hospital, University of Copenhagen, 4200 Slagelse, Denmark.ORCID 0000-0002-0763-5637
Niels HøibyDepartment of Clinical Microbiology, Rigshospitalet, University of Copenhagen, 2100 Copenhagen, Denmark.
Peter Østrup JensenDepartment of Clinical Microbiology, Rigshospitalet, University of Copenhagen, 2100 Copenhagen, Denmark.ORCID 0000-0003-1648-7186
Oana CiofuCosterton Biofilm Center, Department of Immunology and Microbiology, University of Copenhagen, 2200 Copenhagen, Denmark.
Claus MoserDepartment of Clinical Microbiology, Rigshospitalet, University of Copenhagen, 2100 Copenhagen, Denmark.
University of Copenhagen · DK

Funding

Novo Nordisk Foundation NNF17OC0025074
6 · The paper itself

Abstract

Biofilm infections are tolerant to the host responses and recalcitrance to antibiotic drugs and disinfectants. The induced host-specific innate and adaptive immune responses by established biofilms are significantly implicated and contributes to the course of the infections. Essentially, the host response may be the single one factor impacting the outcome most, especially in cases where the biofilm is caused by low virulent opportunistic bacterial species. Due to the chronicity of biofilm infections, activation of the adaptive immune response mechanisms is frequently experienced, and instead of clearing the infection, the adaptive response adds to the pathogenesis. To a high degree, this has been reported for chronic

Indexed as

biofilmsimmunologyinflammationlung infectionPseudomonas aeruginosa

Identifiers

PMID36140163
PMCPMC9495460
OpenAlexW4293009032

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.