Evidence map›Paper›PMID 36140120›Full record

ArticleBiosensors2022

Biosensing Chlorpyrifos in Environmental Water Samples by a Newly Developed Carbon Nanoparticle-Based Indirect Lateral Flow Assay.

Linda Willemsen, Jan Wichers, Mang Xu, Richard Van Hoof, Coby Van Dooremalen, Aart Van Amerongen, Jeroen Peters

Open access · goldAbstract read
In one paragraph

Article in Biosensors, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
4.8field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 26 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Linda WillemsenWageningen Food Safety Research, 6708 WB Wageningen, The Netherlands.
Jan WichersWageningen Food & Biobased Research, 6708 WG Wageningen, The Netherlands.
Mang XuWageningen Food Safety Research, 6708 WB Wageningen, The Netherlands.
Richard Van HoofWageningen Food Safety Research, 6708 WB Wageningen, The Netherlands.
Coby Van DooremalenWageningen Plant Research, 6708 PB Wageningen, The Netherlands.ORCID 0000-0002-1525-0171
Aart Van AmerongenWageningen Food & Biobased Research, 6708 WG Wageningen, The Netherlands.ORCID 0000-0002-2502-5744
Jeroen PetersWageningen Food Safety Research, 6708 WB Wageningen, The Netherlands.ORCID 0000-0003-0982-1473
Wageningen University & Research · NL

Funding

European Union 817622
6 · The paper itself

Abstract

Pesticides are used in agriculture to prevent pests. Chlorpyrifos (CHLP) is an insecticide with potentially detrimental effects on humans, bees, and the aquatic environment. Its effects have led to a total ban by the European Union (EU), but outside the EU, CHLP is still produced and used. An indirect lateral flow immunoassay (LFIA) for the detection of CHLP was developed and integrated into a cassette to create a lateral flow device (LFD). Species-specific reporter antibodies were coupled to carbon nanoparticles to create a detector conjugate. Water samples were mixed with a specific CHLP monoclonal antibody and detector conjugate and applied to the LFD. Dose-response curves elicited the detection of low concentrations of CHLP (<1 µg/L). This sensitivity was recorded through a rapid handheld digital imaging device but also visually by naked eye. The CHLP LFD was applied to a range of European surface water samples, fortified with CHLP, revealing a sensitivity in these matrices of 2 µg/L, both by digital and visual analysis. To improve the simplicity of the CHLP LFIA, the assay reagents were dried in tubes, enabling to carry out the test by simply adding water samples and inserting the LFIA strips. This CHLP LFIA is thus suited for the on-site screening of surface waters.

Indexed as

ChlorpyrifosInsecticidesNanoparticlesAnimalsAntibodies, MonoclonalCarbonHumansImmunoassayLimit of DetectionWaterAntibodies, MonoclonalCarbonChlorpyrifosInsecticidesWaterbeeschlorpyrifosenvironmenthoneyimmunoassaylateral flowon-sitesurface water

Identifiers

PMID36140120
PMCPMC9496275
OpenAlexW4295106633

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.