Evidence map›Paper›PMID 36140104›Full record

ArticleBiosensors2022

Biosensing Dopamine and L-Epinephrine with Laccase (

Mariya Pimpilova, Kalina Kamarska, Nina Dimcheva

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In one paragraph

Article in Biosensors, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Mariya PimpilovaFaculty of Chemistry, University of Plovdiv "Paisii Hilendarski", 24, Tsar Assen St., 4000 Plovdiv, Bulgaria.ORCID 0000-0002-6105-2715
Kalina KamarskaLaboratory on Biosensors, Centre for Competence PERIMED, University of Plovdiv, 21, Kostaki Peev St., 4000 Plovdiv, Bulgaria.
Nina DimchevaFaculty of Chemistry, University of Plovdiv "Paisii Hilendarski", 24, Tsar Assen St., 4000 Plovdiv, Bulgaria.ORCID 0000-0001-7082-8266

Funding

European Fund for Regional Development; European Social Fund: BG Programme "Science and Education for Smart Growth" BG05M2OP001-1.002-0005-C01
6 · The paper itself

Abstract

Engineering electrode surfaces through the electrodeposition of gold may provide a range of advantages in the context of biosensor development, such as greatly enhanced surface area, improved conductivity and versatile functionalization. In this work we report on the development of an electrochemical biosensor for the laccase-catalyzed assay of two catecholamines-dopamine and L-epinephrine. Variety of electrochemical techniques-cyclic voltammetry, differential pulse voltammetry, electrochemical impedance spectroscopy and constant potential amperometry have been used in its characterization. It has been demonstrated that the laccase electrode is capable of sensing dopamine using two distinct techniques-differential pulse voltammetry and constant potential amperometry, the latter being suitable for the assay of L-epinephrine as well. The biosensor response to both catecholamines, examined by constant potential chronoamperometry over the potential range from 0.2 to -0.1 V (vs. Ag|AgCl, sat KCl) showed the highest electrode sensitivity at 0 and -0.1 V. The dependencies of the current density on either catecholamine's concentration was found to follow the Michaelis-Menten kinetics with apparent constants

Indexed as

Biosensing TechniquesGoldDopamineElectrodesEnzymes, ImmobilizedEpinephrineLaccasePharmaceutical PreparationsPolyporaceaeTrametesDopamineEnzymes, ImmobilizedEpinephrineGoldLaccasePharmaceutical Preparationscovalent bindingdopamineelectrodeposited porous goldlaccase from Trametes pubescensL-epinephrinemediated electron transfer (MET)

Identifiers

PMID36140104
PMCPMC9496072

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.