Evidence map›Paper›PMID 36140086›Full record

ArticleBiosensors2022

Screening of Single-Stranded DNA Aptamer Specific for Florfenicol and Application in Detection of Food Safety.

Minghui Shi, Ruobing Liu, Fuyuan Zhang, Bimal Chitrakar, Xianghong Wang

Abstract read
In one paragraph

Article in Biosensors, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
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  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Minghui ShiCollege of Food Science and Technology, Hebei Agricultural University, Baoding 071001, China.
Ruobing LiuCollege of Food Science and Technology, Hebei Agricultural University, Baoding 071001, China.
Fuyuan ZhangCollege of Food Science and Technology, Hebei Agricultural University, Baoding 071001, China.
Bimal ChitrakarCollege of Food Science and Technology, Hebei Agricultural University, Baoding 071001, China.ORCID 0000-0001-7444-9255
Xianghong WangCollege of Food Science and Technology, Hebei Agricultural University, Baoding 071001, China.

Funding

Thirteenth Five-Year" National Key R&D Program Key Projects 2019YFD0902003
6 · The paper itself

Abstract

In this work, the single-stranded DNA (ssDNA) aptamers specific to florfenicol (FF) and having a high binding affinity were prepared using the magnetic bead-based systematic evolution of ligands by the exponential enrichment technique (MB-SELEX). After 10 rounds of the MB-SELEX screening, aptamers that can simultaneously recognize FF and its metabolite florfenicol amine (FFA) were obtained. The aptamer with the lowest dissociation constant (K

Indexed as

Aptamers, NucleotideDNA, Single-StrandedFood SafetyLigandsMolecular Docking SimulationSELEX Aptamer TechniqueThiamphenicolAptamers, NucleotideDNA, Single-StrandedflorfenicolLigandsThiamphenicolaptamerAuNPsflorfenicolmolecular dockingSELEX

Identifiers

PMID36140086
PMCPMC9496042

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.