Evidence map›Paper›PMID 36140007›Full record

ArticleAntibiotics (Basel, Switzerland)2022

Impact of an Antimicrobial Stewardship Program Intervention Associated with the Rapid Identification of Microorganisms by MALDI-TOF and Detection of Resistance Genes in ICU Patients with Gram-Negative Bacteremia.

Aléia Faustina Campos, Tiago Arantes, Amanda Magalhães Vilas Boas Cambiais, Ana Paula Cury, Camila Guimarães Tiroli, Flávia Rossi, Luiz Marcelo Sa Malbouisson, Silvia Figueiredo Costa, Thaís Guimarães

Open access · goldAbstract read
In one paragraph

Article in Antibiotics (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
1.3field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 11 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Rapid diagnostics and ceftazidime/avibactam for KPC-producing Klebsiella pneumoniae bloodstream infections: impact on mortality and role of combination therapy.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2023
    Observational
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Aléia Faustina CamposDepartment of Infection Control, Instituto Central, Hospital das Clínicas, University of São Paulo, São Paulo 05508-220, Brazil.ORCID 0000-0002-3244-5237
Tiago ArantesPharmacy Division, Hospital das Clínicas, University of São Paulo, São Paulo 05508-220, Brazil.ORCID 0000-0003-3542-7197
Amanda Magalhães Vilas Boas CambiaisPharmacy Division, Hospital das Clínicas, University of São Paulo, São Paulo 05508-220, Brazil.
Ana Paula CuryMicrobiology Laboratory, Central Laboratory Division, Hospital das Clínicas, University of São Paulo, São Paulo 05508-220, Brazil.
Camila Guimarães TiroliMicrobiology Laboratory, Central Laboratory Division, Hospital das Clínicas, University of São Paulo, São Paulo 05508-220, Brazil.
Flávia RossiMicrobiology Laboratory, Central Laboratory Division, Hospital das Clínicas, University of São Paulo, São Paulo 05508-220, Brazil.
Luiz Marcelo Sa MalbouissonDivision of Anesthesiology, Hospital das Clínicas, University of São Paulo, São Paulo 05508-220, Brazil.ORCID 0000-0002-3261-5603
Silvia Figueiredo CostaInfectious Diseases Department, Hospital das Clínicas, University of São Paulo, São Paulo 05508-220, Brazil.
Thaís GuimarãesDepartment of Infection Control, Instituto Central, Hospital das Clínicas, University of São Paulo, São Paulo 05508-220, Brazil.ORCID 0000-0002-7282-5453
Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo · BR

Funding

São Paulo Research Foundation 2018/24021-0
6 · The paper itself

Abstract

Combination of strategies for rapid diagnostics tests (RDT) with real-time intervention could improve patient outcomes. We aimed to assess the impact on clinical outcomes, antimicrobial consumption, and costs in patients with gram-negative bacteremia. We designed a quasi-experimental study among 216 episodes of gram-negative bacteremia using RDT (MALDI-TOF and detection of resistance genes) directly from blood culture bottles combined with real-time communication of results. Our study did not demonstrate impact on 30-day mortality (25% vs. 35%;

Indexed as

antimicrobial consumptionantimicrobial stewardshipdays of therapygram-negative bacteremiamortalityrapid diagnostics tests

Identifiers

PMID36140007
PMCPMC9495121
OpenAlexW4295548766

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.