Evidence map›Paper›PMID 36139979›Full record

ArticleAntibiotics (Basel, Switzerland)2022

In Vitro and In Vivo Antimicrobial Activity of the Novel Peptide OMN6 against Multidrug-Resistant

Janna Michaeli, Shira Mandel, Shelly Maximov, Jonathan Zazoun, Paola Savoia, Nimmi Kothari, Thomas Valmont, Livia Ferrari, Leonard R Duncan, Stephen Hawser and 2 more

Abstract read
In one paragraph

Article in Antibiotics (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Drug-resistantClinical microbiology reviews · 2025
    Pooled it
  2. Review
  3. Review
  4. Treating Extensively Drug-ResistantPathogens (Basel, Switzerland) · 2026
    Review
  5. Article
  6. Review
  7. Microorganisms · 2025
    Review
  8. Review
  9. Review
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Janna MichaeliOmnix Medical Ltd., High-Tech Village, Givat-Ram Campus, Jerusalem 9270401, Israel.
Shira MandelOmnix Medical Ltd., High-Tech Village, Givat-Ram Campus, Jerusalem 9270401, Israel.
Shelly MaximovOmnix Medical Ltd., High-Tech Village, Givat-Ram Campus, Jerusalem 9270401, Israel.
Jonathan ZazounOmnix Medical Ltd., High-Tech Village, Givat-Ram Campus, Jerusalem 9270401, Israel.ORCID 0000-0001-8200-5160
Paola SavoiaEvotec Anti-Infective, Department of Microbiology Discovery, Aptuit (Verona) Srl, an Evotec Company, Via A. Fleming 4, 37135 Verona, Italy.
Nimmi KothariIHMA Europe Sàrl, Route de l'Ile-au-Bois 1A, 1870 Monthey, Switzerland.
Thomas ValmontIHMA Europe Sàrl, Route de l'Ile-au-Bois 1A, 1870 Monthey, Switzerland.
Livia FerrariEvotec Anti-Infective, Department of Microbiology Discovery, Aptuit (Verona) Srl, an Evotec Company, Via A. Fleming 4, 37135 Verona, Italy.
Leonard R DuncanJMI Laboratories, 345 Beaver Kreek Centre, Suite A, North Liberty, IA 52317, USA.
Stephen HawserIHMA Europe Sàrl, Route de l'Ile-au-Bois 1A, 1870 Monthey, Switzerland.
Moshe Cohen-KutnerOmnix Medical Ltd., High-Tech Village, Givat-Ram Campus, Jerusalem 9270401, Israel.
Niv BachnoffOmnix Medical Ltd., High-Tech Village, Givat-Ram Campus, Jerusalem 9270401, Israel.

Funding

Israeli Innovative Authority XXX
6 · The paper itself

Abstract

The rapid worldwide spread of antimicrobial resistance highlights the significant need for the development of innovative treatments to fight multidrug-resistant bacteria. This study describes the potent antimicrobial activity of the novel peptide OMN6 against a wide array of drug-resistant

Indexed as

Acinetobacter baumanniiAMRantimicrobial peptidesantimicrobial resistanceinfectious diseasesOMN6

Identifiers

PMID36139979
PMCPMC9494975

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.