Evidence map›Paper›PMID 36139901›Full record

ArticleAntioxidants (Basel, Switzerland)2022

Antioxidant Potential of the Sweet Whey-Based Beverage

Victoria E García-Casas, Isabel Seiquer, Zaira Pardo, Ana Haro, Isidra Recio, Raquel Olías

Open access · goldAbstract read
In one paragraph

Article in Antioxidants (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.1field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 15 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Victoria E García-CasasFacultad de Ingeniería Química, Universidad de Guayaquil, Ciudadela Universitaria, Avenida Delta S/N y Avenida Kennedy, Guayaquil 090514, Ecuador.
Isabel SeiquerDepartamento Nutrición y Producción Animal Sostenible, Estación Experimental del Zaidín, Consejo Superior de Investigaciones Científicas (CSIC), San Miguel 101, Armilla, 18100 Granada, Spain.ORCID 0000-0003-2984-8673
Zaira PardoDepartamento Nutrición y Producción Animal Sostenible, Estación Experimental del Zaidín, Consejo Superior de Investigaciones Científicas (CSIC), San Miguel 101, Armilla, 18100 Granada, Spain.
Ana HaroDepartamento Nutrición y Producción Animal Sostenible, Estación Experimental del Zaidín, Consejo Superior de Investigaciones Científicas (CSIC), San Miguel 101, Armilla, 18100 Granada, Spain.ORCID 0000-0001-9865-0850
Isidra RecioInstituto de Investigación en Ciencias de la Alimentación, CIAL (CSIC-UAM, CEI UAM+CSIC), Nicolás Cabrera, 9, 28049 Madrid, Spain.ORCID 0000-0003-2973-5329
Raquel OlíasDepartamento Nutrición y Producción Animal Sostenible, Estación Experimental del Zaidín, Consejo Superior de Investigaciones Científicas (CSIC), San Miguel 101, Armilla, 18100 Granada, Spain.
Consejo Superior de Investigaciones Científicas · ESInstituto de Investigación en Ciencias de la Alimentación · ESUniversity of Guayaquil · EC

Funding

Spanish National Research Council 00001Spanish National Research Council own funds
6 · The paper itself

Abstract

Whey-based beverages could be an effective way of reusing a by-product of th cheese industry, mitigating environmental hazards and, at the same time, profiting a useful food with high nutritional and antioxidant properties. In this study, a traditional Ecuadorian beverage (Colada) was prepared combining sweet whey, Maracuyá and barley. Antioxidant properties before and after an in vitro digestion using the INFOGEST method were determined, and relationships with intestinal transformations of the lipid and protein fractions were analyzed. The digestive process had a positive effect on antioxidant properties based on increased values of ABTS and FRAP located in the bioaccessible fraction (BF), together with strong increments of total polyphenols. Moreover, pretreatment of Caco-2 cells with the BF of Colada significantly reduced ROS generation (p < 0.001) measured by the dichlorofluorescein assay. Substantial changes of the fatty acid profile occurred during digestion, such as a fall of saturated fatty acids and a rise of polyunsaturated. The protein profile, examined by SDS-PAGE and exclusion molecular chromatography in the BF, showed that the major part of the proteins were digested in the intestinal phase. Analysis of NanoLC-MS/MS revealed 18 antioxidant peptides originated from whey proteins, but also 16 peptides from barley with potential antioxidant properties. In conclusion, combining sweet whey with Maracuyá and barley constitutes an excellent nutritional beverage with a strong antioxidant potential.

Indexed as

antioxidant activityantioxidant peptidesfatty acidsin vitro digestionprotein profilesweet wheywhey beverages

Identifiers

PMID36139901
PMCPMC9495724
OpenAlexW4296312419

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.