Evidence map›Paper›PMID 36139852›Full record

ArticleAntioxidants (Basel, Switzerland)2022

Influence of Simulated In Vitro Gastrointestinal Digestion on the Phenolic Profile, Antioxidant, and Biological Activity of

Farah Diab, Mohamad Khalil, Giulio Lupidi, Hawraa Zbeeb, Annalisa Salis, Gianluca Damonte, Massimo Bramucci, Piero Portincasa, Laura Vergani

Open access · goldAbstract read
In one paragraph

Article in Antioxidants (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.3field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 17 citations in OpenAlex.

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  9. Effect ofPreventive nutrition and food science · 2023
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Farah DiabDepartment of Earth, Environment and Life Sciences (DISTAV), University of Genova, Corso Europa 26, 16132 Genova, Italy.ORCID 0000-0002-4488-5547
Mohamad KhalilClinica Medica "A. Murri", Department of Biomedical Sciences and Human Oncology, Medical School, University of Bari "Aldo Moro", 70124 Bari, Italy.ORCID 0000-0002-5943-9531
Giulio LupidiSchool of Pharmacy, University of Camerino, 62032 Camerino, Italy.
Hawraa ZbeebDepartment of Earth, Environment and Life Sciences (DISTAV), University of Genova, Corso Europa 26, 16132 Genova, Italy.ORCID 0000-0002-1451-6441
Annalisa SalisDepartment of Experimental Medicine (DIMES), University of Genova, Viale Benedetto XV 1, 16132 Genova, Italy.ORCID 0000-0002-3082-2908
Gianluca DamonteDepartment of Experimental Medicine (DIMES), University of Genova, Viale Benedetto XV 1, 16132 Genova, Italy.ORCID 0000-0001-8769-2051
Massimo BramucciSchool of Pharmacy, University of Camerino, 62032 Camerino, Italy.ORCID 0000-0003-4113-8199
Piero PortincasaClinica Medica "A. Murri", Department of Biomedical Sciences and Human Oncology, Medical School, University of Bari "Aldo Moro", 70124 Bari, Italy.ORCID 0000-0001-5359-1471
Laura VerganiDepartment of Earth, Environment and Life Sciences (DISTAV), University of Genova, Corso Europa 26, 16132 Genova, Italy.ORCID 0000-0002-1268-4724
University of Genoa · ITUniversità di Camerino · ITUniversity of Bari Aldo Moro · IT

Funding

University of Genoa FRA 2020 and 2021
6 · The paper itself

Abstract

Plants or plant extracts are widely investigated for preventing/counteracting several chronic disorders. The oral route is the most common route for nutraceutical and drug administration. Currently, it is still unclear as to whether and how the pattern of phenolic compounds (PCs) found in the plants as well as their bioactivity could be modified during the gastrointestinal transit. Recent studies have revealed antioxidant and anti-steatotic properties of Thymbra spicata. Here, we investigated the possible loss of phytochemicals that occurs throughout the sequential steps of a simulated in vitro gastrointestinal (GI) digestion of aqueous and ethanolic extracts of aerial parts of

Indexed as

antioxidant capacitycytotoxic effectin vitro gastrointestinal digestionphytochemical characterizationThymbra spicata L. extracts

Identifiers

PMID36139852
PMCPMC9495638
OpenAlexW4295211046

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.