Evidence map›Paper›PMID 36139835›Full record

ArticleAntioxidants (Basel, Switzerland)2022

Antitumor Potential of Withanolide Glycosides from Ashwagandha (

Dahae Lee, Jae Sik Yu, Ji Won Ha, Seoung Rak Lee, Bum Soo Lee, Jin-Chul Kim, Jung Kyu Kim, Ki Sung Kang, Ki Hyun Kim

Open access · goldAbstract read
In one paragraph

Article in Antioxidants (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
5.6field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 19 citations in OpenAlex.

  1. Nutraceutical Applications ofFoods (Basel, Switzerland) · 2026
    Review
  2. Article
  3. 1,3,5-Tricaffeoylquinic Acid fromBiomolecules & therapeutics · 2025
    Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Review
  9. Review
  10. Can Ashwagandha Benefit the Endocrine System?-A Review.International journal of molecular sciences · 2023
    Review
  11. Molecules (Basel, Switzerland) · 2023
    Article
  12. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Dahae LeeCollege of Korean Medicine, Gachon University, Seongnam 13120, Korea.
Jae Sik YuSchool of Pharmacy, Sungkyunkwan University, Suwon 16419, Korea.ORCID 0000-0002-3320-4662
Ji Won HaSchool of Pharmacy, Sungkyunkwan University, Suwon 16419, Korea.
Seoung Rak LeeSchool of Pharmacy, Sungkyunkwan University, Suwon 16419, Korea.
Bum Soo LeeSchool of Pharmacy, Sungkyunkwan University, Suwon 16419, Korea.
Jin-Chul KimKIST Gangneung Institute of Natural Products, Natural Product Informatics Research Center, Gangneung 25451, Korea.ORCID 0000-0002-2535-2761
Jung Kyu KimSchool of Chemical Engineering, Sungkyunkwan University, Suwon 16419, Korea.ORCID 0000-0002-8218-0062
Ki Sung KangCollege of Korean Medicine, Gachon University, Seongnam 13120, Korea.
Ki Hyun KimSchool of Pharmacy, Sungkyunkwan University, Suwon 16419, Korea.ORCID 0000-0002-5285-9138
Sungkyunkwan University · KRGachon University · KRSejong University · KR

Funding

Korea Institute of Science and Technology 2E31881National Research Foundation of Korea 2019R1A5A2027340 and 2021R1A2C2007937
6 · The paper itself

Abstract

Hepatocellular carcinoma (HCC) is the fastest-growing tumor capable of spreading to other organs via blood vessels formed by endothelial cells. Apoptosis and angiogenesis-targeting therapies are attractive for cancer treatment. In this study, we aimed to study the in vitro cytotoxicity of

Indexed as

angiogenesisapoptosishepatocellular carcinomaHepG2 cellsWithania somniferawithanolide glycosides

Identifiers

PMID36139835
PMCPMC9495654
OpenAlexW4296793606

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.